Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 4564984..4565206 Replicon chromosome
Accession NZ_AP022351
Organism Escherichia coli strain E138

Toxin (Protein)


Gene name ldrD Uniprot ID A0A3K0NFU8
Locus tag GR930_RS22085 Protein ID WP_000170748.1
Coordinates 4564984..4565091 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 4565148..4565206 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GR930_RS22060 4560519..4560707 - 189 WP_001063314.1 YhjR family protein -
GR930_RS22065 4560980..4562551 + 1572 WP_001204941.1 cellulose biosynthesis protein BcsE -
GR930_RS22070 4562548..4562739 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
GR930_RS22075 4562736..4564415 + 1680 Protein_4296 cellulose biosynthesis protein BcsG -
GR930_RS22080 4564501..4564608 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
GR930_RS22085 4564984..4565091 - 108 WP_000170748.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 4565148..4565206 + 59 - - Antitoxin
GR930_RS22090 4565467..4565574 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
GR930_RS22095 4566050..4567321 + 1272 WP_001545666.1 amino acid permease -
GR930_RS22100 4567338..4568345 - 1008 WP_001262467.1 HipA domain-containing protein -
GR930_RS22105 4568345..4568656 - 312 WP_001312177.1 HipA N-terminal domain-containing protein -
GR930_RS22110 4568641..4568964 - 324 WP_000563102.1 helix-turn-helix transcriptional regulator -
GR930_RS22115 4569189..4570202 - 1014 WP_000103572.1 dipeptide ABC transporter ATP-binding subunit DppF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3913.76 Da        Isoelectric Point: 9.0157

>T35440 WP_000170748.1 NZ_AP022351:c4565091-4564984 [Escherichia coli]
MTLAELGMAFWHDLAVPVITGILASMIVSWLNKRK

Download         Length: 108 bp

>T35440 NZ_AP022351:c4565091-4564984 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGTTCCGGTCATTACTGGCATTCTTGCCAGTATGAT
CGTGAGCTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 59 bp

>AT35440 NZ_AP022351:4565148-4565206 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3K0NFU8

Antitoxin

Download structure file

References