Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1924139..1924695 Replicon chromosome
Accession NZ_AP022347
Organism Fluviibacter phosphoraccumulans strain ICHIJ1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag ICHIJ1_RS12205 Protein ID WP_202930750.1
Coordinates 1924513..1924695 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag ICHIJ1_RS09670 Protein ID WP_162050402.1
Coordinates 1924139..1924453 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICHIJ1_RS09650 1919289..1920434 + 1146 WP_162050398.1 transglutaminase-like domain-containing protein -
ICHIJ1_RS09655 1920454..1920834 + 381 WP_162050399.1 hypothetical protein -
ICHIJ1_RS09660 1920988..1921587 + 600 WP_162050400.1 hypothetical protein -
ICHIJ1_RS09665 1921613..1924075 - 2463 WP_162050401.1 replicative DNA helicase -
ICHIJ1_RS09670 1924139..1924453 - 315 WP_162050402.1 transcriptional regulator Antitoxin
ICHIJ1_RS12205 1924513..1924695 - 183 WP_202930750.1 hypothetical protein Toxin
ICHIJ1_RS09680 1924882..1925331 - 450 WP_162050403.1 50S ribosomal protein L9 -
ICHIJ1_RS09685 1925337..1925624 - 288 WP_162050404.1 30S ribosomal protein S18 -
ICHIJ1_RS09690 1925646..1925942 - 297 WP_162050975.1 primosomal replication protein N -
ICHIJ1_RS09695 1925974..1926330 - 357 WP_162050405.1 30S ribosomal protein S6 -
ICHIJ1_RS09700 1926417..1927370 - 954 WP_162050406.1 CysB family HTH-type transcriptional regulator -
ICHIJ1_RS09705 1927486..1928259 + 774 WP_162050976.1 sulfite exporter TauE/SafE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-101)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6815.79 Da        Isoelectric Point: 9.5057

>T35407 WP_202930750.1 NZ_AP022347:c1924695-1924513 [Fluviibacter phosphoraccumulans]
MATPEAGDVIEGTGGLRKLRYADATRGKGKRGGLRVIYYWWVSGAQFWLFTLYNKDEMVD

Download         Length: 183 bp

>T35407 NZ_AP022347:c1924695-1924513 [Fluviibacter phosphoraccumulans]
ATGGCTACGCCAGAAGCCGGTGATGTCATTGAAGGCACTGGCGGTCTTAGAAAGCTAAGGTATGCCGATGCGACTAGAGG
AAAAGGTAAGCGTGGCGGTCTGAGAGTAATTTACTACTGGTGGGTGTCTGGTGCGCAGTTCTGGCTATTTACGCTGTACA
ACAAAGATGAAATGGTGGATTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11900.80 Da        Isoelectric Point: 10.9823

>AT35407 WP_162050402.1 NZ_AP022347:c1924453-1924139 [Fluviibacter phosphoraccumulans]
MTKRNMFAELVEGFEALAEHREGKRTLRTHKVAAKAIDAIAPDELVRLRERLHLSRPVFATCLRTNPRTLENWEQGRAKP
NAQATVLIRLVEKFPDTVQRLASV

Download         Length: 315 bp

>AT35407 NZ_AP022347:c1924453-1924139 [Fluviibacter phosphoraccumulans]
ATGACCAAAAGAAATATGTTTGCAGAGTTGGTAGAGGGGTTTGAAGCCTTGGCTGAGCACCGGGAGGGGAAGCGTACGCT
GCGAACCCATAAGGTTGCTGCAAAAGCGATCGACGCAATTGCGCCGGATGAGCTCGTGCGTCTTAGAGAACGTTTGCACT
TATCCCGTCCGGTTTTTGCCACCTGCTTGAGGACGAATCCCAGAACTTTGGAGAATTGGGAGCAAGGGCGGGCAAAGCCG
AATGCGCAGGCGACGGTGTTGATCCGTTTGGTCGAAAAGTTTCCTGATACGGTTCAGCGACTGGCATCGGTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References