Detailed information of TA system TA035389

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 1960029..1960555
• Replicon: chromosome
• Accession: NZ_AP022345
• Organism: Fluviibacter phosphoraccumulans strain ICHIAU1

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: ICHIAU1_RS09725
• Protein ID: WP_162049678.1
• Coordinates: 1960029..1960295 (-)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: ICHIAU1_RS09730
• Protein ID: WP_162049677.1
• Coordinates: 1960295..1960555 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ICHIAU1_RS09690	1955185..1955985	-	801	WP_162049683.1	3'(2'),5'-bisphosphate nucleotidase CysQ	-
ICHIAU1_RS09695	1955988..1956587	-	600	WP_162049682.1	adenylyl-sulfate kinase	-
ICHIAU1_RS09700	1956594..1956872	-	279	WP_162049681.1	type II toxin-antitoxin system RelE/ParE family toxin	-
ICHIAU1_RS09705	1956872..1957138	-	267	WP_162049680.1	ribbon-helix-helix protein, CopG family	-
ICHIAU1_RS09710	1957205..1958509	-	1305	WP_202930690.1	glycosyltransferase family 4 protein	-
ICHIAU1_RS09715	1958524..1959471	-	948	WP_202930691.1	hypothetical protein	-
ICHIAU1_RS09720	1959490..1959960	-	471	WP_162049679.1	hypothetical protein	-
ICHIAU1_RS09725	1960029..1960295	-	267	WP_162049678.1	Txe/YoeB family addiction module toxin	Toxin
ICHIAU1_RS09730	1960295..1960555	-	261	WP_162049677.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
ICHIAU1_RS09735	1960781..1961440	-	660	WP_162049676.1	transcriptional regulator	-
ICHIAU1_RS09740	1961446..1962450	-	1005	WP_162049675.1	glycosyl transferase	-
ICHIAU1_RS09745	1962533..1962811	-	279	WP_162049674.1	plasmid stabilization protein	-
ICHIAU1_RS09750	1962808..1963065	-	258	WP_162049673.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
ICHIAU1_RS09755	1963133..1963999	-	867	WP_162049672.1	hypothetical protein	-
ICHIAU1_RS09760	1964077..1964532	-	456	WP_162049671.1	protein-export chaperone SecB	-
ICHIAU1_RS09765	1964529..1965188	-	660	WP_162049670.1	type II toxin-antitoxin system MqsA family antitoxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	fcl / gmd	1951104..1994441	43337

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-75)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10276.69 Da
• Isoelectric Point: 7.9860

>T35389 WP_162049678.1 NZ_AP022345:c1960295-1960029 [Fluviibacter phosphoraccumulans]
MARDIRFVPDAWADYLYWQEQDKKTLKRLNTLITGAARDPFVGIGKPEPLRGDLSGYWSRRIDDVNRLVYRATDTDLVII
ACRFHYDG

Nucleotide

• Length: 267 bp

>T35389 NZ_AP022345:c1960295-1960029 [Fluviibacter phosphoraccumulans]
ATGGCTCGTGACATCCGTTTTGTCCCGGACGCATGGGCTGATTATCTGTATTGGCAAGAGCAGGACAAGAAGACGCTGAA
AAGATTGAATACTTTGATCACTGGCGCTGCACGTGACCCGTTTGTTGGTATAGGCAAACCGGAACCCTTACGTGGCGATT
TGTCAGGCTATTGGTCAAGACGGATCGATGATGTTAACCGCCTGGTTTATCGTGCAACCGATACGGATTTGGTGATTATT
GCGTGTCGGTTTCACTACGATGGTTGA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9176.31 Da
• Isoelectric Point: 4.4536

>AT35389 WP_162049677.1 NZ_AP022345:c1960555-1960295 [Fluviibacter phosphoraccumulans]
MKVVTYSEARNALKSILDGVVSDADVTIISRRDAEGDAVVMSLDSYNSIMETLHLTSNPANAAALARAIAQDKAGQVQVR
QLLSDD

Nucleotide

• Length: 261 bp

>AT35389 NZ_AP022345:c1960555-1960295 [Fluviibacter phosphoraccumulans]
ATGAAAGTGGTGACTTATTCTGAGGCACGTAACGCGCTGAAGTCTATTTTGGATGGTGTGGTGTCGGATGCCGATGTAAC
GATCATTAGTCGTCGTGATGCCGAGGGTGATGCGGTTGTGATGTCGTTAGATAGCTACAACAGCATTATGGAAACCCTGC
ACCTCACCAGTAATCCTGCTAACGCTGCGGCTTTGGCCCGTGCCATTGCCCAGGATAAAGCTGGCCAGGTGCAGGTGCGC
CAGCTGCTGTCGGATGATTAA