Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/- |
Location | 1164015..1164571 | Replicon | chromosome |
Accession | NZ_AP022345 | ||
Organism | Fluviibacter phosphoraccumulans strain ICHIAU1 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | ICHIAU1_RS12000 | Protein ID | WP_202930750.1 |
Coordinates | 1164015..1164197 (+) | Length | 61 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | ICHIAU1_RS05785 | Protein ID | WP_162050402.1 |
Coordinates | 1164257..1164571 (+) | Length | 105 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ICHIAU1_RS05750 | 1160451..1161224 | - | 774 | WP_162050976.1 | sulfite exporter TauE/SafE family protein | - |
ICHIAU1_RS05755 | 1161340..1162293 | + | 954 | WP_162050406.1 | CysB family HTH-type transcriptional regulator | - |
ICHIAU1_RS05760 | 1162380..1162736 | + | 357 | WP_162050405.1 | 30S ribosomal protein S6 | - |
ICHIAU1_RS05765 | 1162768..1163064 | + | 297 | WP_162050975.1 | primosomal replication protein N | - |
ICHIAU1_RS05770 | 1163086..1163373 | + | 288 | WP_162050404.1 | 30S ribosomal protein S18 | - |
ICHIAU1_RS05775 | 1163379..1163828 | + | 450 | WP_162050403.1 | 50S ribosomal protein L9 | - |
ICHIAU1_RS12000 | 1164015..1164197 | + | 183 | WP_202930750.1 | hypothetical protein | Toxin |
ICHIAU1_RS05785 | 1164257..1164571 | + | 315 | WP_162050402.1 | transcriptional regulator | Antitoxin |
ICHIAU1_RS05790 | 1164635..1167097 | + | 2463 | WP_162050401.1 | replicative DNA helicase | - |
ICHIAU1_RS05795 | 1167123..1167722 | - | 600 | WP_162050400.1 | hypothetical protein | - |
ICHIAU1_RS05800 | 1167876..1168256 | - | 381 | WP_162050399.1 | hypothetical protein | - |
ICHIAU1_RS05805 | 1168276..1169421 | - | 1146 | WP_162050398.1 | transglutaminase-like domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6815.79 Da Isoelectric Point: 9.5057
>T35381 WP_202930750.1 NZ_AP022345:1164015-1164197 [Fluviibacter phosphoraccumulans]
MATPEAGDVIEGTGGLRKLRYADATRGKGKRGGLRVIYYWWVSGAQFWLFTLYNKDEMVD
MATPEAGDVIEGTGGLRKLRYADATRGKGKRGGLRVIYYWWVSGAQFWLFTLYNKDEMVD
Download Length: 183 bp
>T35381 NZ_AP022345:1164015-1164197 [Fluviibacter phosphoraccumulans]
ATGGCTACGCCAGAAGCCGGTGATGTCATTGAAGGCACTGGCGGTCTTAGAAAGCTAAGGTATGCCGATGCGACTAGAGG
AAAAGGTAAGCGTGGCGGTCTGAGAGTAATTTACTACTGGTGGGTGTCTGGTGCGCAGTTCTGGCTATTTACGCTGTACA
ACAAAGATGAAATGGTGGATTGA
ATGGCTACGCCAGAAGCCGGTGATGTCATTGAAGGCACTGGCGGTCTTAGAAAGCTAAGGTATGCCGATGCGACTAGAGG
AAAAGGTAAGCGTGGCGGTCTGAGAGTAATTTACTACTGGTGGGTGTCTGGTGCGCAGTTCTGGCTATTTACGCTGTACA
ACAAAGATGAAATGGTGGATTGA
Antitoxin
Download Length: 105 a.a. Molecular weight: 11900.80 Da Isoelectric Point: 10.9823
>AT35381 WP_162050402.1 NZ_AP022345:1164257-1164571 [Fluviibacter phosphoraccumulans]
MTKRNMFAELVEGFEALAEHREGKRTLRTHKVAAKAIDAIAPDELVRLRERLHLSRPVFATCLRTNPRTLENWEQGRAKP
NAQATVLIRLVEKFPDTVQRLASV
MTKRNMFAELVEGFEALAEHREGKRTLRTHKVAAKAIDAIAPDELVRLRERLHLSRPVFATCLRTNPRTLENWEQGRAKP
NAQATVLIRLVEKFPDTVQRLASV
Download Length: 315 bp
>AT35381 NZ_AP022345:1164257-1164571 [Fluviibacter phosphoraccumulans]
ATGACCAAAAGAAATATGTTTGCAGAGTTGGTAGAGGGGTTTGAAGCCTTGGCTGAGCACCGGGAGGGGAAGCGTACGCT
GCGAACCCATAAGGTTGCTGCAAAAGCGATCGACGCAATTGCGCCGGATGAGCTCGTGCGTCTTAGAGAACGTTTGCACT
TATCCCGTCCGGTTTTTGCCACCTGCTTGAGGACGAATCCCAGAACTTTGGAGAATTGGGAGCAAGGGCGGGCAAAGCCG
AATGCGCAGGCGACGGTGTTGATCCGTTTGGTCGAAAAGTTTCCTGATACGGTTCAGCGACTGGCATCGGTCTAA
ATGACCAAAAGAAATATGTTTGCAGAGTTGGTAGAGGGGTTTGAAGCCTTGGCTGAGCACCGGGAGGGGAAGCGTACGCT
GCGAACCCATAAGGTTGCTGCAAAAGCGATCGACGCAATTGCGCCGGATGAGCTCGTGCGTCTTAGAGAACGTTTGCACT
TATCCCGTCCGGTTTTTGCCACCTGCTTGAGGACGAATCCCAGAACTTTGGAGAATTGGGAGCAAGGGCGGGCAAAGCCG
AATGCGCAGGCGACGGTGTTGATCCGTTTGGTCGAAAAGTTTCCTGATACGGTTCAGCGACTGGCATCGGTCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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