Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1164015..1164571 Replicon chromosome
Accession NZ_AP022345
Organism Fluviibacter phosphoraccumulans strain ICHIAU1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag ICHIAU1_RS12000 Protein ID WP_202930750.1
Coordinates 1164015..1164197 (+) Length 61 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag ICHIAU1_RS05785 Protein ID WP_162050402.1
Coordinates 1164257..1164571 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICHIAU1_RS05750 1160451..1161224 - 774 WP_162050976.1 sulfite exporter TauE/SafE family protein -
ICHIAU1_RS05755 1161340..1162293 + 954 WP_162050406.1 CysB family HTH-type transcriptional regulator -
ICHIAU1_RS05760 1162380..1162736 + 357 WP_162050405.1 30S ribosomal protein S6 -
ICHIAU1_RS05765 1162768..1163064 + 297 WP_162050975.1 primosomal replication protein N -
ICHIAU1_RS05770 1163086..1163373 + 288 WP_162050404.1 30S ribosomal protein S18 -
ICHIAU1_RS05775 1163379..1163828 + 450 WP_162050403.1 50S ribosomal protein L9 -
ICHIAU1_RS12000 1164015..1164197 + 183 WP_202930750.1 hypothetical protein Toxin
ICHIAU1_RS05785 1164257..1164571 + 315 WP_162050402.1 transcriptional regulator Antitoxin
ICHIAU1_RS05790 1164635..1167097 + 2463 WP_162050401.1 replicative DNA helicase -
ICHIAU1_RS05795 1167123..1167722 - 600 WP_162050400.1 hypothetical protein -
ICHIAU1_RS05800 1167876..1168256 - 381 WP_162050399.1 hypothetical protein -
ICHIAU1_RS05805 1168276..1169421 - 1146 WP_162050398.1 transglutaminase-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-101)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6815.79 Da        Isoelectric Point: 9.5057

>T35381 WP_202930750.1 NZ_AP022345:1164015-1164197 [Fluviibacter phosphoraccumulans]
MATPEAGDVIEGTGGLRKLRYADATRGKGKRGGLRVIYYWWVSGAQFWLFTLYNKDEMVD

Download         Length: 183 bp

>T35381 NZ_AP022345:1164015-1164197 [Fluviibacter phosphoraccumulans]
ATGGCTACGCCAGAAGCCGGTGATGTCATTGAAGGCACTGGCGGTCTTAGAAAGCTAAGGTATGCCGATGCGACTAGAGG
AAAAGGTAAGCGTGGCGGTCTGAGAGTAATTTACTACTGGTGGGTGTCTGGTGCGCAGTTCTGGCTATTTACGCTGTACA
ACAAAGATGAAATGGTGGATTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11900.80 Da        Isoelectric Point: 10.9823

>AT35381 WP_162050402.1 NZ_AP022345:1164257-1164571 [Fluviibacter phosphoraccumulans]
MTKRNMFAELVEGFEALAEHREGKRTLRTHKVAAKAIDAIAPDELVRLRERLHLSRPVFATCLRTNPRTLENWEQGRAKP
NAQATVLIRLVEKFPDTVQRLASV

Download         Length: 315 bp

>AT35381 NZ_AP022345:1164257-1164571 [Fluviibacter phosphoraccumulans]
ATGACCAAAAGAAATATGTTTGCAGAGTTGGTAGAGGGGTTTGAAGCCTTGGCTGAGCACCGGGAGGGGAAGCGTACGCT
GCGAACCCATAAGGTTGCTGCAAAAGCGATCGACGCAATTGCGCCGGATGAGCTCGTGCGTCTTAGAGAACGTTTGCACT
TATCCCGTCCGGTTTTTGCCACCTGCTTGAGGACGAATCCCAGAACTTTGGAGAATTGGGAGCAAGGGCGGGCAAAGCCG
AATGCGCAGGCGACGGTGTTGATCCGTTTGGTCGAAAAGTTTCCTGATACGGTTCAGCGACTGGCATCGGTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References