33683

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1103319..1103974 Replicon chromosome
Accession NZ_AP021904
Organism Pseudomonas sp. Ost2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KI243_RS04800 Protein ID WP_177085445.1
Coordinates 1103630..1103974 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag KI243_RS04795 Protein ID WP_017123749.1
Coordinates 1103319..1103633 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI243_RS04770 (PHLH7_09300) 1098971..1100173 + 1203 WP_212810560.1 ROK family transcriptional regulator -
KI243_RS04775 (PHLH7_09310) 1100259..1100936 + 678 WP_212810561.1 metallophosphoesterase -
KI243_RS04780 (PHLH7_09320) 1100947..1101171 - 225 WP_017123752.1 hypothetical protein -
KI243_RS04785 (PHLH7_09330) 1101349..1102665 + 1317 WP_177119242.1 PAS domain-containing methyl-accepting chemotaxis protein -
KI243_RS04790 (PHLH7_09340) 1102760..1103242 - 483 WP_017123750.1 RidA family protein -
KI243_RS04795 (PHLH7_09350) 1103319..1103633 - 315 WP_017123749.1 transcriptional regulator Antitoxin
KI243_RS04800 (PHLH7_09360) 1103630..1103974 - 345 WP_177085445.1 toxin Toxin
KI243_RS04805 (PHLH7_09370) 1104143..1105030 + 888 WP_017123747.1 Dyp-type peroxidase -
KI243_RS04810 (PHLH7_09380) 1105282..1105740 + 459 WP_017123746.1 hypothetical protein -
KI243_RS04815 (PHLH7_09390) 1105777..1106499 - 723 WP_017123745.1 polyphenol oxidase family protein -
KI243_RS04820 (PHLH7_09400) 1106643..1107737 + 1095 WP_042934434.1 D-alanine--D-alanine ligase -
KI243_RS04825 (PHLH7_09410) 1107811..1108851 + 1041 WP_212810562.1 DMT family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13417.39 Da        Isoelectric Point: 9.7103

>T33683 WP_177085445.1 NZ_AP021904:c1103974-1103630 [Pseudomonas sp. Ost2]
MKSVFFETSQFTATVSHYLTDDEYRQLQLEMQANPHAGDVMPRTGGFRKIRWPDVRRGKGKRGGLRIIYYWLLECGQFWM
FAIYDKGELENLTPHQENMLKTAIDAELKRRGKT

Download         Length: 345 bp

>T33683 NZ_AP021904:c1103974-1103630 [Pseudomonas sp. Ost2]
ATGAAATCCGTATTCTTCGAAACATCACAGTTCACTGCCACGGTGAGTCATTACCTTACCGATGACGAATATCGACAACT
CCAACTCGAGATGCAGGCCAATCCTCATGCAGGAGATGTCATGCCTCGCACAGGAGGTTTTCGCAAAATACGCTGGCCCG
ATGTTCGAAGAGGCAAGGGCAAGCGTGGTGGCTTGCGGATCATCTATTACTGGCTGCTGGAGTGTGGCCAGTTCTGGATG
TTCGCTATCTATGACAAAGGCGAGCTGGAAAACCTGACACCACACCAGGAAAACATGCTGAAAACGGCGATTGATGCCGA
ATTGAAGCGACGAGGTAAAACATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12065.14 Da        Isoelectric Point: 9.2223

>AT33683 WP_017123749.1 NZ_AP021904:c1103633-1103319 [Pseudomonas sp. Ost2]
MKKRDLFAELMQGVTEMAEHREGKITLRHCELEELPPPVVTAQEIVALREKLHMSQPVFAHRIRTSPDTLKNWEQAKSRP
NAQAALLIKLVERFPDMIERLRAV

Download         Length: 315 bp

>AT33683 NZ_AP021904:c1103633-1103319 [Pseudomonas sp. Ost2]
ATGAAAAAGCGCGATCTGTTTGCCGAACTGATGCAAGGCGTCACAGAAATGGCCGAACATCGCGAAGGTAAAATCACCCT
TCGTCACTGTGAGCTGGAAGAGCTACCGCCCCCAGTCGTCACAGCGCAGGAAATTGTCGCTTTGCGAGAAAAGCTGCACA
TGTCACAACCGGTTTTTGCCCACCGGATTCGAACCAGTCCCGATACGCTCAAGAACTGGGAGCAAGCCAAATCCCGGCCC
AACGCTCAGGCAGCGCTGCTGATCAAACTCGTGGAGCGCTTTCCCGACATGATTGAGCGTCTGAGAGCCGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References