Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 3206489..3207002 Replicon chromosome
Accession NZ_AP021881
Organism Sulfuriferula nivalis strain SGTM

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag SFSGTM_RS15825 Protein ID WP_162085998.1
Coordinates 3206489..3206755 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag SFSGTM_RS15830 Protein ID WP_162085999.1
Coordinates 3206748..3207002 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SFSGTM_RS15805 3201894..3202502 + 609 WP_162085994.1 5-formyltetrahydrofolate cyclo-ligase -
SFSGTM_RS15810 3202489..3203019 - 531 WP_162085995.1 phosphatase PAP2 family protein -
SFSGTM_RS15815 3202985..3204202 - 1218 WP_162085996.1 glycosyltransferase family 1 protein -
SFSGTM_RS15820 3204299..3206482 + 2184 WP_162085997.1 primosomal protein N' -
SFSGTM_RS15825 3206489..3206755 - 267 WP_162085998.1 Txe/YoeB family addiction module toxin Toxin
SFSGTM_RS15830 3206748..3207002 - 255 WP_162085999.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
SFSGTM_RS15835 3207086..3208081 - 996 WP_162086000.1 integron integrase -
SFSGTM_RS15840 3208876..3209910 - 1035 Protein_3113 transposase -
SFSGTM_RS15845 3209907..3210134 - 228 WP_198420638.1 tyrosine-type recombinase/integrase -
SFSGTM_RS15850 3210074..3210742 - 669 WP_162083789.1 tyrosine-type recombinase/integrase -
SFSGTM_RS15855 3211022..3211249 + 228 WP_162086001.1 hypothetical protein -
SFSGTM_RS15860 3211340..3211993 + 654 WP_162086002.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10439.94 Da        Isoelectric Point: 8.4590

>T33496 WP_162085998.1 NZ_AP021881:c3206755-3206489 [Sulfuriferula nivalis]
MISRLTWTLASWDDYVYWQGQDKKTLKRINQLIQATMRQPFEGIGKPEPLKENLAGYWSRRIDETNRLVYCVNEGDLVII
ACRYHYGN

Download         Length: 267 bp

>T33496 NZ_AP021881:c3206755-3206489 [Sulfuriferula nivalis]
ATGATTAGTCGGCTGACCTGGACACTGGCATCCTGGGATGATTATGTTTATTGGCAAGGTCAGGACAAAAAGACGCTTAA
ACGCATCAATCAGCTTATTCAGGCAACAATGCGGCAACCGTTTGAAGGCATAGGTAAGCCAGAACCATTAAAAGAGAACT
TGGCAGGTTACTGGTCACGCAGAATTGATGAAACTAATCGCTTGGTGTACTGCGTAAACGAAGGTGATTTGGTTATCATT
GCCTGCCGCTATCACTACGGCAACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9206.41 Da        Isoelectric Point: 4.6676

>AT33496 WP_162085999.1 NZ_AP021881:c3207002-3206748 [Sulfuriferula nivalis]
MRVMNFSEARSSLKAVIDQVVDDADYTVIARRDAPDAVIMSLDAFNGLMETVHLLKSPANAAHLANSIAQYQQGKTVSRE
LVDD

Download         Length: 255 bp

>AT33496 NZ_AP021881:c3207002-3206748 [Sulfuriferula nivalis]
ATGCGTGTCATGAATTTTTCTGAAGCTCGTAGCAGTTTAAAAGCGGTGATCGATCAAGTTGTTGATGATGCTGATTACAC
CGTCATTGCTCGACGCGATGCGCCCGATGCGGTGATTATGTCGTTAGATGCCTTTAATGGCTTAATGGAAACCGTGCATT
TATTAAAATCCCCTGCTAATGCAGCGCATTTGGCAAACTCAATTGCACAATATCAACAAGGCAAAACCGTATCCCGAGAA
CTGGTAGATGATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References