Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 4715528..4716030 Replicon chromosome
Accession NZ_AP021879
Organism Desulfosarcina ovata subsp. ovata strain oXyS1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag GN112_RS20895 Protein ID WP_155311989.1
Coordinates 4715528..4715782 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GN112_RS20900 Protein ID WP_155311990.1
Coordinates 4715779..4716030 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN112_RS20870 4710808..4711821 + 1014 WP_155308523.1 site-specific integrase -
GN112_RS20875 4711845..4712615 - 771 WP_174247668.1 group II intron reverse transcriptase/maturase -
GN112_RS20880 4713417..4713965 + 549 WP_155311986.1 hypothetical protein -
GN112_RS20885 4714119..4714958 + 840 WP_155311987.1 methyltransferase domain-containing protein -
GN112_RS20890 4715096..4715308 + 213 WP_155311988.1 hypothetical protein -
GN112_RS20895 4715528..4715782 - 255 WP_155311989.1 Txe/YoeB family addiction module toxin Toxin
GN112_RS20900 4715779..4716030 - 252 WP_155311990.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
GN112_RS20905 4716294..4718141 + 1848 WP_155311991.1 hypothetical protein -
GN112_RS20910 4718542..4718832 + 291 WP_155311992.1 hypothetical protein -
GN112_RS20915 4719063..4719500 + 438 WP_155311993.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10193.66 Da        Isoelectric Point: 10.0159

>T33454 WP_155311989.1 NZ_AP021879:c4715782-4715528 [Desulfosarcina ovata subsp. ovata]
VKLIFSDNAWDDYIYWQKTDKKILRRINTLIKETKRSPFEGVGKPEPLKHALSGYWSRRINDEHRFVYKVSEDAIHIAQL
RYHY

Download         Length: 255 bp

>T33454 NZ_AP021879:c4715782-4715528 [Desulfosarcina ovata subsp. ovata]
GTGAAGCTCATTTTCTCAGACAATGCCTGGGACGATTACATCTATTGGCAAAAAACTGACAAAAAAATTCTCCGCCGTAT
AAACACTCTGATAAAGGAAACAAAACGCTCTCCTTTTGAAGGTGTTGGCAAACCCGAACCTCTGAAACATGCGCTTTCCG
GCTATTGGTCCAGGCGAATCAATGACGAGCACAGATTCGTTTATAAAGTTTCAGAAGATGCAATTCATATTGCACAACTG
AGATATCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9459.83 Da        Isoelectric Point: 4.8897

>AT33454 WP_155311990.1 NZ_AP021879:c4716030-4715779 [Desulfosarcina ovata subsp. ovata]
MEAITYTAARQNLAKTMEKVCRDRAPIIVTRKSSESVVIMSLEDYEALEETAYLLRSPKNTRRLIESIAQLENGKGDEKE
LIE

Download         Length: 252 bp

>AT33454 NZ_AP021879:c4716030-4715779 [Desulfosarcina ovata subsp. ovata]
ATGGAAGCCATAACCTATACAGCGGCAAGGCAAAACCTTGCGAAAACAATGGAAAAAGTTTGCAGAGACCGTGCCCCGAT
AATTGTTACACGTAAATCCTCTGAATCTGTAGTTATTATGTCCCTTGAGGACTATGAAGCCCTTGAAGAGACTGCTTACC
TTTTACGGTCACCCAAAAACACAAGACGTCTAATTGAATCCATTGCTCAACTTGAAAATGGCAAAGGTGATGAAAAGGAG
CTCATAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References