Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 5760822..5761324 Replicon chromosome
Accession NZ_AP021876
Organism Desulfosarcina ovata subsp. sediminis strain 28bB2T

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag GN113_RS25300 Protein ID WP_155311989.1
Coordinates 5760822..5761076 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GN113_RS25305 Protein ID WP_155311990.1
Coordinates 5761073..5761324 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN113_RS25275 5756868..5757959 + 1092 WP_155324425.1 hypothetical protein -
GN113_RS25280 5758087..5758689 - 603 WP_173179819.1 VCBS repeat-containing protein -
GN113_RS25285 5758892..5759671 + 780 WP_155311979.1 transposase -
GN113_RS25290 5759839..5760222 + 384 WP_155324427.1 hypothetical protein -
GN113_RS25295 5760390..5760602 + 213 WP_155324428.1 hypothetical protein -
GN113_RS25300 5760822..5761076 - 255 WP_155311989.1 Txe/YoeB family addiction module toxin Toxin
GN113_RS25305 5761073..5761324 - 252 WP_155311990.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
GN113_RS25310 5761588..5763435 + 1848 WP_155311991.1 hypothetical protein -
GN113_RS25315 5763837..5764127 + 291 WP_155311992.1 hypothetical protein -
GN113_RS25320 5764359..5764796 + 438 WP_155311993.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10193.66 Da        Isoelectric Point: 10.0159

>T33435 WP_155311989.1 NZ_AP021876:c5761076-5760822 [Desulfosarcina ovata subsp. sediminis]
VKLIFSDNAWDDYIYWQKTDKKILRRINTLIKETKRSPFEGVGKPEPLKHALSGYWSRRINDEHRFVYKVSEDAIHIAQL
RYHY

Download         Length: 255 bp

>T33435 NZ_AP021876:c5761076-5760822 [Desulfosarcina ovata subsp. sediminis]
GTGAAGCTCATTTTCTCAGACAATGCCTGGGACGATTACATCTATTGGCAAAAAACTGACAAAAAAATTCTCCGCCGTAT
AAACACTCTGATAAAGGAAACAAAACGCTCTCCTTTTGAGGGTGTTGGCAAACCCGAACCTCTGAAACATGCGCTTTCCG
GCTATTGGTCCAGGCGAATCAATGACGAGCACAGATTCGTTTATAAAGTTTCAGAAGATGCAATTCATATTGCACAACTG
AGATATCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9459.83 Da        Isoelectric Point: 4.8897

>AT33435 WP_155311990.1 NZ_AP021876:c5761324-5761073 [Desulfosarcina ovata subsp. sediminis]
MEAITYTAARQNLAKTMEKVCRDRAPIIVTRKSSESVVIMSLEDYEALEETAYLLRSPKNTRRLIESIAQLENGKGDEKE
LIE

Download         Length: 252 bp

>AT33435 NZ_AP021876:c5761324-5761073 [Desulfosarcina ovata subsp. sediminis]
ATGGAAGCCATAACCTATACAGCGGCAAGGCAAAACCTTGCGAAAACAATGGAAAAAGTTTGCAGAGACCGTGCCCCGAT
AATTGTTACACGTAAATCCTCTGAATCTGTAGTTATTATGTCCCTTGAGGACTATGAAGCCCTTGAAGAGACTGCTTACC
TTTTACGGTCACCCAAAAACACAAGACGTCTAATTGAATCCATTGCTCAACTTGAAAATGGCAAAGGTGATGAAAAGGAG
CTCATAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References