Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2745798..2746076 Replicon chromosome
Accession NZ_AP020324
Organism Staphylococcus aureus strain KUN1163

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag KUH140013_RS13945 Protein ID WP_001802298.1
Coordinates 2745798..2745902 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2745898..2746076 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KUH140013_RS13920 2742595..2743377 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
KUH140013_RS13925 2743445..2744302 + 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
KUH140013_RS13935 2744960..2745118 - 159 WP_001792784.1 hypothetical protein -
KUH140013_RS13945 2745798..2745902 + 105 WP_001802298.1 hypothetical protein Toxin
- 2745898..2746076 - 179 - - Antitoxin
KUH140013_RS13950 2746335..2747426 - 1092 WP_000495669.1 hypothetical protein -
KUH140013_RS13955 2747692..2748669 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
KUH140013_RS13960 2748671..2748991 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
KUH140013_RS13965 2749143..2749808 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T33355 WP_001802298.1 NZ_AP020324:2745798-2745902 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T33355 NZ_AP020324:2745798-2745902 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT33355 NZ_AP020324:c2746076-2745898 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References