Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 175928..176108 Replicon chromosome
Accession NZ_AP020322
Organism Staphylococcus aureus strain KUH180129

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag F6Y14_RS01150 Protein ID WP_001801861.1
Coordinates 176013..176108 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 175928..175985 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F6Y14_RS01120 171636..171770 + 135 WP_001791797.1 hypothetical protein -
F6Y14_RS01125 171934..173490 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
F6Y14_RS01130 173483..174631 + 1149 WP_150073882.1 restriction endonuclease subunit S -
F6Y14_RS01135 175165..175659 + 495 Protein_175 transposase -
F6Y14_RS01140 175650..175811 + 162 Protein_176 transposase -
F6Y14_RS01145 175789..175890 - 102 WP_001792025.1 hypothetical protein -
- 175928..175985 + 58 - - Antitoxin
F6Y14_RS01150 176013..176108 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
F6Y14_RS01155 176253..177265 + 1013 Protein_179 IS3 family transposase -
F6Y14_RS01160 177463..178035 - 573 WP_000414216.1 hypothetical protein -
F6Y14_RS01165 178136..178477 - 342 WP_000627540.1 DUF3969 family protein -
F6Y14_RS01170 178518..179144 - 627 WP_000669024.1 hypothetical protein -
F6Y14_RS01175 179219..180214 - 996 WP_000070642.1 DUF4352 domain-containing protein -
F6Y14_RS01180 180295..180945 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk / hlgA / lukD 147754..201458 53704


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T33321 WP_001801861.1 NZ_AP020322:c176108-176013 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T33321 NZ_AP020322:c176108-176013 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT33321 NZ_AP020322:175928-175985 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References