Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1709838..1710100 Replicon chromosome
Accession NZ_AP020320
Organism Staphylococcus aureus strain KUH180062

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag F6Y17_RS08880 Protein ID WP_001802298.1
Coordinates 1709996..1710100 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 1709838..1710001 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F6Y17_RS08860 1706090..1706755 - 666 WP_001024095.1 SDR family oxidoreductase -
F6Y17_RS08865 1706907..1707227 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
F6Y17_RS08870 1707229..1708206 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
F6Y17_RS08875 1708472..1709563 + 1092 WP_000495669.1 hypothetical protein -
- 1709838..1710001 + 164 - - Antitoxin
F6Y17_RS08880 1709996..1710100 - 105 WP_001802298.1 hypothetical protein Toxin
F6Y17_RS15265 1710617..1710787 + 171 WP_001792292.1 transposase -
F6Y17_RS08890 1710780..1710938 + 159 WP_001792784.1 hypothetical protein -
F6Y17_RS08900 1711596..1712453 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
F6Y17_RS08905 1712521..1713303 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T33308 WP_001802298.1 NZ_AP020320:c1710100-1709996 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T33308 NZ_AP020320:c1710100-1709996 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT33308 NZ_AP020320:1709838-1710001 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References