Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2667247..2667510 Replicon chromosome
Accession NZ_AP020318
Organism Staphylococcus aureus strain KUH180038

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag F6Y16_RS13460 Protein ID WP_001802298.1
Coordinates 2667247..2667351 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2667346..2667510 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F6Y16_RS13435 2662631..2663413 + 783 WP_000908177.1 ABC transporter ATP-binding protein -
F6Y16_RS13440 2663481..2664338 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
F6Y16_RS13445 2665043..2665135 - 93 WP_001790138.1 hypothetical protein -
F6Y16_RS13450 2665424..2666560 + 1137 WP_000115564.1 SAP domain-containing protein -
F6Y16_RS13455 2666603..2667086 + 484 Protein_2544 recombinase family protein -
F6Y16_RS13460 2667247..2667351 + 105 WP_001802298.1 hypothetical protein Toxin
- 2667346..2667510 - 165 - - Antitoxin
F6Y16_RS13465 2667851..2668942 - 1092 WP_000495671.1 lytic regulatory protein -
F6Y16_RS13470 2669208..2670188 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
F6Y16_RS13475 2670190..2670510 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
F6Y16_RS13480 2670662..2671327 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T33289 WP_001802298.1 NZ_AP020318:2667247-2667351 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T33289 NZ_AP020318:2667247-2667351 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT33289 NZ_AP020318:c2667510-2667346 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References