Detailed information of TA system TA033281

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 200593..200775
• Replicon: chromosome
• Accession: NZ_AP020318
• Organism: Staphylococcus aureus strain KUH180038

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: F6Y16_RS01245
• Protein ID: WP_001801861.1
• Coordinates: 200680..200775 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	200593..200652 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F6Y16_RS01230	199731..200108	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
F6Y16_RS01235	200302..200478	+	177	Protein_194	transposase	-
F6Y16_RS01240	200456..200557	-	102	WP_001791893.1	hypothetical protein	-
-	200593..200652	+	60	-	-	Antitoxin
F6Y16_RS01245	200680..200775	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
F6Y16_RS01255	200978..201121	+	144	WP_001549059.1	transposase	-
F6Y16_RS01265	201725..202108	+	384	WP_000070811.1	hypothetical protein	-
F6Y16_RS01270	202119..202295	+	177	WP_000375476.1	hypothetical protein	-
F6Y16_RS01275	202297..202482	+	186	WP_000809857.1	hypothetical protein	-
F6Y16_RS01280	202596..203237	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
F6Y16_RS01285	203455..204006	-	552	WP_000414205.1	hypothetical protein	-
F6Y16_RS01290	204104..204448	-	345	WP_000627551.1	DUF3969 family protein	-
F6Y16_RS01295	204489..205115	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T33281 WP_001801861.1 NZ_AP020318:c200775-200680 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T33281 NZ_AP020318:c200775-200680 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT33281 NZ_AP020318:200593-200652 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin