Detailed information of TA system TA033267

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2319043..2319227
• Replicon: chromosome
• Accession: NZ_AP020316
• Organism: Staphylococcus aureus strain KUH140331

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: F6Y18_RS11515
• Protein ID: WP_072467491.1
• Coordinates: 2319043..2319150 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2319167..2319227 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F6Y18_RS11490	2314416..2314889	+	474	WP_000456489.1	GyrI-like domain-containing protein	-
F6Y18_RS11495	2315012..2316223	-	1212	WP_001192075.1	multidrug effflux MFS transporter	-
F6Y18_RS11500	2316405..2317064	-	660	WP_000831298.1	membrane protein	-
F6Y18_RS11505	2317124..2318266	-	1143	WP_001176873.1	glycerate kinase	-
F6Y18_RS11510	2318523..2318909	+	387	WP_000779348.1	flippase GtxA	-
F6Y18_RS11515	2319043..2319150	+	108	WP_072467491.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2319167..2319227	-	61	-	-	Antitoxin
F6Y18_RS11520	2319740..2321503	+	1764	WP_001064834.1	ABC transporter ATP-binding protein/permease	-
F6Y18_RS11525	2321528..2323261	+	1734	WP_000486502.1	ABC transporter ATP-binding protein/permease	-
F6Y18_RS11530	2323492..2323659	+	168	WP_031866196.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3944.67 Da
• Isoelectric Point: 10.4934

>T33267 WP_072467491.1 NZ_AP020316:2319043-2319150 [Staphylococcus aureus]
IFNLLIDIMTSAISGCLVAFFANWLRTRSNKKGDK

Nucleotide

• Length: 108 bp

>T33267 NZ_AP020316:2319043-2319150 [Staphylococcus aureus]
ATCTTCAATTTATTAATTGACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCAAATTGGTTACGAAC
GCGCAGCAATAAAAAAGGTGACAAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT33267 NZ_AP020316:c2319227-2319167 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin