Detailed information of TA system TA033263

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 166143..166323
• Replicon: chromosome
• Accession: NZ_AP020316
• Organism: Staphylococcus aureus strain KUH140331

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: F6Y18_RS01080
• Protein ID: WP_001801861.1
• Coordinates: 166228..166323 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	166143..166200 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F6Y18_RS01050	162494..163612	+	1119	WP_000072558.1	restriction endonuclease subunit S	-
F6Y18_RS01055	164260..164703	+	444	WP_000742594.1	DUF1433 domain-containing protein	-
F6Y18_RS01060	164913..165260	+	348	WP_001566695.1	DUF1433 domain-containing protein	-
F6Y18_RS01065	165282..165656	+	375	WP_000695818.1	DUF1433 domain-containing protein	-
F6Y18_RS01070	165844..166026	+	183	Protein_166	transposase	-
F6Y18_RS01075	166004..166105	-	102	WP_001791232.1	hypothetical protein	-
-	166143..166200	+	58	-	-	Antitoxin
F6Y18_RS01080	166228..166323	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
F6Y18_RS01090	166775..167221	+	447	WP_000747802.1	DUF1433 domain-containing protein	-
F6Y18_RS01095	167906..168289	+	384	WP_000070811.1	hypothetical protein	-
F6Y18_RS01100	168300..168476	+	177	WP_000375476.1	hypothetical protein	-
F6Y18_RS01110	168847..169404	+	558	WP_000864138.1	ImmA/IrrE family metallo-endopeptidase	-
F6Y18_RS13915	169602..170174	-	573	Protein_173	hypothetical protein	-
F6Y18_RS01115	170275..170616	-	342	WP_000627548.1	DUF3969 family protein	-
F6Y18_RS01120	170657..171283	-	627	WP_000669019.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	144606..192141	47535

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T33263 WP_001801861.1 NZ_AP020316:c166323-166228 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T33263 NZ_AP020316:c166323-166228 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT33263 NZ_AP020316:166143-166200 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin