Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2670001..2670264 Replicon chromosome
Accession NZ_AP020313
Organism Staphylococcus aureus strain KUH140046

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag F6Y15_RS13485 Protein ID WP_001802298.1
Coordinates 2670001..2670105 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2670100..2670264 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F6Y15_RS13460 2665385..2666167 + 783 WP_000908177.1 ABC transporter ATP-binding protein -
F6Y15_RS13465 2666235..2667092 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
F6Y15_RS13470 2667797..2667889 - 93 WP_001790138.1 hypothetical protein -
F6Y15_RS13475 2668178..2669314 + 1137 WP_000115564.1 SAP domain-containing protein -
F6Y15_RS13480 2669357..2669840 + 484 Protein_2552 recombinase family protein -
F6Y15_RS13485 2670001..2670105 + 105 WP_001802298.1 hypothetical protein Toxin
- 2670100..2670264 - 165 - - Antitoxin
F6Y15_RS13490 2670605..2671696 - 1092 WP_000495671.1 lytic regulatory protein -
F6Y15_RS13495 2671962..2672942 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
F6Y15_RS13500 2672944..2673264 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
F6Y15_RS13505 2673416..2674081 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T33253 WP_001802298.1 NZ_AP020313:2670001-2670105 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T33253 NZ_AP020313:2670001-2670105 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT33253 NZ_AP020313:c2670264-2670100 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References