Detailed information of TA system TA033245

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 202159..202341
• Replicon: chromosome
• Accession: NZ_AP020313
• Organism: Staphylococcus aureus strain KUH140046

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: F6Y15_RS01255
• Protein ID: WP_001801861.1
• Coordinates: 202246..202341 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	202159..202218 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F6Y15_RS01240	201297..201674	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
F6Y15_RS01245	201868..202044	+	177	Protein_198	transposase	-
F6Y15_RS01250	202022..202123	-	102	WP_001791893.1	hypothetical protein	-
-	202159..202218	+	60	-	-	Antitoxin
F6Y15_RS01255	202246..202341	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
F6Y15_RS01265	202544..202687	+	144	WP_001549059.1	transposase	-
F6Y15_RS01275	203291..203674	+	384	WP_000070811.1	hypothetical protein	-
F6Y15_RS01280	203685..203861	+	177	WP_000375476.1	hypothetical protein	-
F6Y15_RS01285	203863..204048	+	186	WP_000809857.1	hypothetical protein	-
F6Y15_RS01290	204162..204803	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
F6Y15_RS01295	205021..205572	-	552	WP_000414205.1	hypothetical protein	-
F6Y15_RS01300	205670..206014	-	345	WP_000627551.1	DUF3969 family protein	-
F6Y15_RS01305	206055..206681	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	183644..229110	45466

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T33245 WP_001801861.1 NZ_AP020313:c202341-202246 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T33245 NZ_AP020313:c202341-202246 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT33245 NZ_AP020313:202159-202218 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin