Detailed information of TA system TA033227

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 186457..186639
• Replicon: chromosome
• Accession: NZ_AP020311
• Organism: Staphylococcus aureus strain KUH140013

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: F6Y13_RS01170
• Protein ID: WP_001801861.1
• Coordinates: 186544..186639 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	186457..186516 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
F6Y13_RS01155	185595..185972	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
F6Y13_RS01160	186166..186342	+	177	Protein_179	transposase	-
F6Y13_RS01165	186320..186421	-	102	WP_001791893.1	hypothetical protein	-
-	186457..186516	+	60	-	-	Antitoxin
F6Y13_RS01170	186544..186639	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
F6Y13_RS01180	186842..186985	+	144	WP_001549059.1	transposase	-
F6Y13_RS01190	187589..187972	+	384	WP_000070811.1	hypothetical protein	-
F6Y13_RS01195	187983..188159	+	177	WP_000375476.1	hypothetical protein	-
F6Y13_RS01200	188161..188346	+	186	WP_000809857.1	hypothetical protein	-
F6Y13_RS01205	188460..189101	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
F6Y13_RS01210	189319..189870	-	552	WP_000414205.1	hypothetical protein	-
F6Y13_RS01215	189968..190312	-	345	WP_000627551.1	DUF3969 family protein	-
F6Y13_RS01220	190353..190979	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	155111..224080	68969

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T33227 WP_001801861.1 NZ_AP020311:c186639-186544 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T33227 NZ_AP020311:c186639-186544 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT33227 NZ_AP020311:186457-186516 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin