Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 300489..301002 Replicon chromosome
Accession NZ_AP019862
Organism Rickettsia heilongjiangensis strain CH8-1

Toxin (Protein)


Gene name yoeB Uniprot ID H6QL72
Locus tag GOZ09_RS01660 Protein ID WP_012152537.1
Coordinates 300742..301002 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A0F3RGJ3
Locus tag GOZ09_RS01655 Protein ID WP_014013992.1
Coordinates 300489..300731 (+) Length 81 a.a.

Genomic Context

GOZ09_RS01640GOZ09_RS01645GOZ09_RS01650GOZ09_RS01655GOZ09_RS01660GOZ09_RS01665GOZ09_RS01670GOZ09_RS01675GOZ09_RS01680GOZ09_RS01635
Location: 297466..297735 (270 bp)
Type: Others
Protein ID: WP_014013989.1
Location: 297890..299260 (1371 bp)
Type: Others
Protein ID: WP_014013990.1
Location: 299268..300287 (1020 bp)
Type: Others
Protein ID: WP_014013991.1
Location: 300489..300731 (243 bp)
Type: Antitoxin
Protein ID: WP_014013992.1
Location: 300742..301002 (261 bp)
Type: Toxin
Protein ID: WP_012152537.1
Location: 300995..301843 (849 bp)
Type: Others
Protein ID: WP_014013993.1
Location: 301920..303158 (1239 bp)
Type: Others
Protein ID: WP_014013994.1
Location: 303312..304022 (711 bp)
Type: Others
Protein ID: WP_014013995.1
Location: 304251..305837 (1587 bp)
Type: Others
Protein ID: WP_014013996.1
Location: 295516..297285 (1770 bp)
Type: Others
Protein ID: WP_014013988.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GOZ09_RS01635295516..297285-1770WP_014013988.1ABC transporter ATP-binding protein/permease-
GOZ09_RS01640297466..297735+270WP_014013989.1DUF2671 domain-containing protein-
GOZ09_RS01645297890..299260+1371WP_014013990.1cytochrome ubiquinol oxidase subunit I-
GOZ09_RS01650299268..300287+1020WP_014013991.1cytochrome d ubiquinol oxidase subunit II-
GOZ09_RS01655300489..300731+243WP_014013992.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
GOZ09_RS01660300742..301002+261WP_012152537.1Txe/YoeB family addiction module toxinToxin
GOZ09_RS01665300995..301843+849WP_014013993.1glycosyltransferase family 2 protein-
GOZ09_RS01670301920..303158+1239WP_014013994.1insulinase family protein-
GOZ09_RS01675303312..304022+711WP_014013995.1phosphoribosylaminoimidazolesuccinocarboxamide synthase-
GOZ09_RS01680304251..305837+1587WP_014013996.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(22-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10314.10 Da        Isoelectric Point: 9.9572

>T33211 WP_012152537.1 NZ_AP019862:300742-301002 [Rickettsia heilongjiangensis]
MYIIRYTTQAQKDAKKIVQAGLKNKVEVLLNIVSTDPWKIYPPYEKLVGDFSGCYSRRINIQHRLVYEVYKQEKVVKILR
MYTHYE

Download         Length: 261 bp

>T33211 NZ_AP019862:300742-301002 [Rickettsia heilongjiangensis]
ATGTATATAATTCGTTATACTACACAAGCACAAAAAGATGCTAAGAAAATAGTGCAAGCCGGTTTAAAGAATAAAGTAGA
AGTTTTATTAAACATAGTTAGTACTGATCCTTGGAAAATTTACCCTCCATATGAAAAGCTCGTTGGTGACTTTAGCGGTT
GTTATTCAAGAAGAATTAATATTCAACATAGGTTGGTTTATGAAGTTTACAAACAAGAAAAAGTTGTAAAAATTCTTAGA
ATGTATACGCATTATGAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9405.83 Da        Isoelectric Point: 7.1617

>AT33211 WP_014013992.1 NZ_AP019862:300489-300731 [Rickettsia heilongjiangensis]
MEIYNTSEARSKLYKLIDYVSDVHKPVYIKGKRNNVVIISEEDYRNMEETLYLLSIPNMHKSLIEGRAEPIAKCSDKLNW

Download         Length: 243 bp

>AT33211 NZ_AP019862:300489-300731 [Rickettsia heilongjiangensis]
ATGGAAATATATAATACAAGCGAAGCAAGAAGTAAGCTTTATAAACTTATAGATTATGTTTCTGATGTACACAAACCTGT
TTATATTAAAGGTAAAAGAAATAATGTAGTTATAATTTCAGAAGAAGATTATCGTAATATGGAAGAAACTTTATATTTAT
TATCTATTCCAAATATGCATAAGTCTCTAATTGAAGGACGCGCAGAGCCTATAGCAAAGTGTAGCGATAAATTAAATTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBH6QL72

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0F3RGJ3

References