Detailed information of TA system TA033159

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 1310512..1311028
• Replicon: chromosome
• Accession: NZ_AP019831
• Organism: Leptotrichia trevisanii strain JMUB3870

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: JMUB4039_RS06010
• Protein ID: WP_155282712.1
• Coordinates: 1310771..1311028 (+)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: JMUB4039_RS06005
• Protein ID: WP_155282711.1
• Coordinates: 1310512..1310769 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JMUB4039_RS06005	1310512..1310769	+	258	WP_155282711.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
JMUB4039_RS06010	1310771..1311028	+	258	WP_155282712.1	Txe/YoeB family addiction module toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-59)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10289.78 Da
• Isoelectric Point: 10.2832

>T33159 WP_155282712.1 NZ_AP019831:1310771-1311028 [Leptotrichia trevisanii]
MNINWNNKAWKEYVEWQSKDKKIVKKINEIIKDIQRNGNEGLNKSETLRHGLSGYWSRRITDRHRFIYKLTENEIVIIAC
ANHYK

Nucleotide

• Length: 258 bp

>T33159 NZ_AP019831:1310771-1311028 [Leptotrichia trevisanii]
ATGAATATAAATTGGAATAACAAAGCATGGAAAGAATACGTAGAATGGCAATCGAAAGATAAAAAAATTGTTAAGAAGAT
TAATGAAATTATTAAAGATATTCAGAGAAATGGGAATGAGGGGTTAAATAAATCTGAGACTTTAAGACATGGGTTAAGTG
GTTACTGGAGCAGAAGGATAACTGACAGGCATAGATTTATTTATAAATTGACTGAAAATGAGATTGTGATAATTGCTTGT
GCCAATCATTATAAATAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10180.54 Da
• Isoelectric Point: 4.7370

>AT33159 WP_155282711.1 NZ_AP019831:1310512-1310769 [Leptotrichia trevisanii]
MIATNYSDIRNNLKKYCDKATRDSETIIITRKNDENVVLMSIDEYNNLMENLYIMSNKDYYNELLKRKEEVEKGKVEKHD
LIEVE

Nucleotide

• Length: 258 bp

>AT33159 NZ_AP019831:1310512-1310769 [Leptotrichia trevisanii]
ATGATAGCTACAAATTATTCTGATATTAGAAATAATCTAAAAAAATATTGTGACAAGGCAACACGAGATTCTGAAACAAT
AATTATAACTAGAAAAAATGATGAAAATGTTGTGTTGATGAGTATAGACGAATACAATAATTTGATGGAAAATTTGTATA
TTATGTCTAATAAGGATTATTATAATGAATTACTTAAAAGAAAGGAAGAAGTTGAAAAAGGGAAAGTTGAAAAACATGAT
TTAATTGAGGTGGAATAA