Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2179204..2179420 Replicon chromosome
Accession NZ_AP019712
Organism Staphylococcus aureus strain Tokyo12480

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag GOZ34_RS10730 Protein ID WP_001802298.1
Coordinates 2179316..2179420 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2179204..2179259 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GOZ34_RS10710 2175341..2176006 - 666 WP_001024099.1 SDR family oxidoreductase -
GOZ34_RS10715 2176158..2176478 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
GOZ34_RS10720 2176480..2177460 + 981 WP_029550399.1 CDF family zinc efflux transporter CzrB -
GOZ34_RS10725 2177726..2178817 + 1092 WP_000495673.1 hypothetical protein -
- 2179204..2179259 + 56 - - Antitoxin
GOZ34_RS10730 2179316..2179420 - 105 WP_001802298.1 hypothetical protein Toxin
GOZ34_RS10735 2180100..2180258 + 159 WP_001792784.1 hypothetical protein -
GOZ34_RS10740 2180916..2181773 - 858 WP_029550401.1 Cof-type HAD-IIB family hydrolase -
GOZ34_RS10745 2181841..2182623 - 783 WP_155978265.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T32925 WP_001802298.1 NZ_AP019712:c2179420-2179316 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T32925 NZ_AP019712:c2179420-2179316 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT32925 NZ_AP019712:2179204-2179259 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References