Detailed information of TA system TA032917

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1000006..1000255
• Replicon: chromosome
• Accession: NZ_AP019712
• Organism: Staphylococcus aureus strain Tokyo12480

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: GOZ34_RS04770
• Protein ID: WP_000623369.1
• Coordinates: 1000006..1000113 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1000108..1000255 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GOZ34_RS04745	996680..997249	-	570	WP_000287265.1	competence protein ComK	-
GOZ34_RS04750	997459..997677	+	219	WP_000876826.1	IDEAL domain-containing protein	-
GOZ34_RS04755	997758..998744	-	987	WP_070973816.1	lipoate--protein ligase	-
GOZ34_RS04760	998943..999119	+	177	WP_000214898.1	YkvS family protein	-
GOZ34_RS04765	999134..999736	+	603	WP_155978071.1	CPBP family intramembrane metalloprotease	-
GOZ34_RS04770	1000006..1000113	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1000108..1000255	-	148	-	-	Antitoxin
GOZ34_RS04775	1000749..1001033	+	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
GOZ34_RS04780	1001077..1003041	+	1965	WP_072511790.1	bacteriocin-associated integral membrane family protein	-
GOZ34_RS04785	1003044..1003364	+	321	WP_000668623.1	YxeA family protein	-
GOZ34_RS04790	1003361..1004002	+	642	WP_000571192.1	ABC transporter ATP-binding protein	-
GOZ34_RS04795	1004090..1004380	-	291	WP_001796515.1	hypothetical protein	-
GOZ34_RS04800	1004470..1004658	+	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
GOZ34_RS04805	1004747..1005103	-	357	WP_000766009.1	DoxX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T32917 WP_000623369.1 NZ_AP019712:1000006-1000113 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T32917 NZ_AP019712:1000006-1000113 [Staphylococcus aureus]
GTGATATCTATTGCAAATGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT32917 NZ_AP019712:c1000255-1000108 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGTAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTGCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin