32754

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2597623..2597807 Replicon chromosome
Accession NZ_AP019545
Organism Staphylococcus aureus strain KG-22

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag GDK20_RS13330 Protein ID WP_000482652.1
Coordinates 2597700..2597807 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2597623..2597683 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GDK20_RS13315 2593078..2593245 - 168 Protein_2509 hypothetical protein -
GDK20_RS13320 2593476..2595209 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
GDK20_RS13325 2595234..2596997 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2597623..2597683 + 61 - - Antitoxin
GDK20_RS13330 2597700..2597807 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
GDK20_RS13335 2597941..2598327 - 387 WP_000779360.1 flippase GtxA -
GDK20_RS13340 2598595..2599737 + 1143 WP_001176863.1 glycerate kinase -
GDK20_RS13345 2599797..2600456 + 660 WP_000831298.1 membrane protein -
GDK20_RS13350 2600638..2601849 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
GDK20_RS13355 2601972..2602445 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T32754 WP_000482652.1 NZ_AP019545:c2597807-2597700 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T32754 NZ_AP019545:c2597807-2597700 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT32754 NZ_AP019545:2597623-2597683 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References