32749

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2307118..2307380 Replicon chromosome
Accession NZ_AP019545
Organism Staphylococcus aureus strain KG-22

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag GDK20_RS11780 Protein ID WP_001802298.1
Coordinates 2307276..2307380 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2307118..2307281 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GDK20_RS11760 2303370..2304035 - 666 WP_001024095.1 SDR family oxidoreductase -
GDK20_RS11765 2304187..2304507 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
GDK20_RS11770 2304509..2305486 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
GDK20_RS11775 2305752..2306843 + 1092 WP_000495669.1 hypothetical protein -
- 2307118..2307281 + 164 - - Antitoxin
GDK20_RS11780 2307276..2307380 - 105 WP_001802298.1 hypothetical protein Toxin
GDK20_RS11790 2308060..2308218 + 159 WP_001792784.1 hypothetical protein -
GDK20_RS11800 2308876..2309733 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
GDK20_RS11805 2309801..2310583 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T32749 WP_001802298.1 NZ_AP019545:c2307380-2307276 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T32749 NZ_AP019545:c2307380-2307276 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT32749 NZ_AP019545:2307118-2307281 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References