Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2309147..2309363 Replicon chromosome
Accession NZ_AP019543
Organism Staphylococcus aureus strain KG-18

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag GDK18_RS11785 Protein ID WP_001802298.1
Coordinates 2309259..2309363 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2309147..2309202 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GDK18_RS11765 2305353..2306018 - 666 WP_001024095.1 SDR family oxidoreductase -
GDK18_RS11770 2306170..2306490 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
GDK18_RS11775 2306492..2307469 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
GDK18_RS11780 2307735..2308826 + 1092 WP_000495669.1 hypothetical protein -
- 2309147..2309202 + 56 - - Antitoxin
GDK18_RS11785 2309259..2309363 - 105 WP_001802298.1 hypothetical protein Toxin
GDK18_RS15365 2309880..2310050 + 171 WP_001792292.1 transposase -
GDK18_RS11795 2310043..2310201 + 159 WP_001792784.1 hypothetical protein -
GDK18_RS11805 2310859..2311716 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
GDK18_RS11810 2311784..2312566 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T32728 WP_001802298.1 NZ_AP019543:c2309363-2309259 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T32728 NZ_AP019543:c2309363-2309259 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT32728 NZ_AP019543:2309147-2309202 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References