Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2293861..2294123 Replicon chromosome
Accession NZ_AP019542
Organism Staphylococcus aureus strain KG-03

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag GDK21_RS11705 Protein ID WP_001802298.1
Coordinates 2294019..2294123 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2293861..2294024 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GDK21_RS11685 2290113..2290778 - 666 WP_001024095.1 SDR family oxidoreductase -
GDK21_RS11690 2290930..2291250 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
GDK21_RS11695 2291252..2292229 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
GDK21_RS11700 2292495..2293586 + 1092 WP_000495669.1 hypothetical protein -
- 2293861..2294024 + 164 - - Antitoxin
GDK21_RS11705 2294019..2294123 - 105 WP_001802298.1 hypothetical protein Toxin
GDK21_RS11715 2294803..2294961 + 159 WP_001792784.1 hypothetical protein -
GDK21_RS11725 2295619..2296476 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
GDK21_RS11730 2296544..2297326 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T32705 WP_001802298.1 NZ_AP019542:c2294123-2294019 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T32705 NZ_AP019542:c2294123-2294019 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT32705 NZ_AP019542:2293861-2294024 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References