Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1190969..1191153 Replicon chromosome
Accession NZ_AP019306
Organism Staphylococcus aureus strain TUM9463

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag EKM74_RS06660 Protein ID WP_000482652.1
Coordinates 1191046..1191153 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1190969..1191029 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EKM74_RS06635 1186424..1186591 - 168 Protein_1212 hypothetical protein -
EKM74_RS06645 1186822..1188555 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
EKM74_RS06650 1188580..1190343 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 1190969..1191029 + 61 - - Antitoxin
EKM74_RS06660 1191046..1191153 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
EKM74_RS06665 1191287..1191673 - 387 WP_000779360.1 flippase GtxA -
EKM74_RS06670 1191941..1193083 + 1143 WP_001176863.1 glycerate kinase -
EKM74_RS06675 1193143..1193802 + 660 WP_000831298.1 membrane protein -
EKM74_RS06680 1193984..1195195 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
EKM74_RS06685 1195318..1195791 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T32605 WP_000482652.1 NZ_AP019306:c1191153-1191046 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T32605 NZ_AP019306:c1191153-1191046 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT32605 NZ_AP019306:1190969-1191029 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References