32581

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1197623..1197807 Replicon chromosome
Accession NZ_AP019305
Organism Staphylococcus aureus strain TUM9458

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag EKM72_RS06695 Protein ID WP_000482652.1
Coordinates 1197700..1197807 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1197623..1197683 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EKM72_RS06670 1193078..1193245 - 168 Protein_1221 hypothetical protein -
EKM72_RS06680 1193476..1195209 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
EKM72_RS06685 1195234..1196997 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 1197623..1197683 + 61 - - Antitoxin
EKM72_RS06695 1197700..1197807 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
EKM72_RS06700 1197941..1198327 - 387 WP_000779360.1 flippase GtxA -
EKM72_RS06705 1198595..1199737 + 1143 WP_001176863.1 glycerate kinase -
EKM72_RS06710 1199797..1200456 + 660 WP_000831298.1 membrane protein -
EKM72_RS06715 1200638..1201849 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
EKM72_RS06720 1201972..1202445 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T32581 WP_000482652.1 NZ_AP019305:c1197807-1197700 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T32581 NZ_AP019305:c1197807-1197700 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT32581 NZ_AP019305:1197623-1197683 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References