Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2270142..2270339 Replicon chromosome
Accession NZ_AP018923
Organism Staphylococcus aureus strain JMUB3031

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag D5070_RS11905 Protein ID WP_001802298.1
Coordinates 2270235..2270339 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2270142..2270180 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D5070_RS11885 2266383..2267048 - 666 WP_001024095.1 SDR family oxidoreductase -
D5070_RS11890 2267200..2267520 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
D5070_RS11895 2267522..2268502 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
D5070_RS11900 2268768..2269859 + 1092 WP_000495683.1 hypothetical protein -
- 2270142..2270180 + 39 - - Antitoxin
D5070_RS11905 2270235..2270339 - 105 WP_001802298.1 hypothetical protein Toxin
D5070_RS11915 2271019..2271177 + 159 WP_001792784.1 hypothetical protein -
D5070_RS11925 2271836..2272693 - 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
D5070_RS11930 2272761..2273543 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T32452 WP_001802298.1 NZ_AP018923:c2270339-2270235 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T32452 NZ_AP018923:c2270339-2270235 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT32452 NZ_AP018923:2270142-2270180 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References