32430

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2144575..2144791 Replicon chromosome
Accession NZ_AP018922
Organism Staphylococcus aureus strain JMUB1273

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag JMUB1273_RS11065 Protein ID WP_001802298.1
Coordinates 2144687..2144791 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2144575..2144630 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMUB1273_RS11045 2140769..2141434 - 666 WP_119267464.1 SDR family oxidoreductase -
JMUB1273_RS11050 2141586..2141906 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
JMUB1273_RS11055 2141908..2142888 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
JMUB1273_RS11060 2143154..2144245 + 1092 WP_000495681.1 hypothetical protein -
- 2144575..2144630 + 56 - - Antitoxin
JMUB1273_RS11065 2144687..2144791 - 105 WP_001802298.1 hypothetical protein Toxin
JMUB1273_RS11075 2145471..2145629 + 159 WP_001792784.1 hypothetical protein -
JMUB1273_RS11085 2146287..2147144 - 858 WP_000370928.1 Cof-type HAD-IIB family hydrolase -
JMUB1273_RS11090 2147212..2147994 - 783 WP_000908189.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T32430 WP_001802298.1 NZ_AP018922:c2144791-2144687 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T32430 NZ_AP018922:c2144791-2144687 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT32430 NZ_AP018922:2144575-2144630 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References