Detailed information of TA system TA032421

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1825031..1825211
• Replicon: chromosome
• Accession: NZ_AP018922
• Organism: Staphylococcus aureus strain JMUB1273

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: JMUB1273_RS09075
• Protein ID: WP_001801861.1
• Coordinates: 1825031..1825126 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1825154..1825211 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JMUB1273_RS09035	1820072..1820698	+	627	WP_000669019.1	hypothetical protein	-
JMUB1273_RS09040	1820739..1821080	+	342	WP_000627548.1	DUF3969 family protein	-
JMUB1273_RS14135	1821181..1821753	+	573	Protein_1702	hypothetical protein	-
JMUB1273_RS09045	1821951..1822508	-	558	WP_000864138.1	ImmA/IrrE family metallo-endopeptidase	-
JMUB1273_RS09055	1822879..1823055	-	177	WP_000375476.1	hypothetical protein	-
JMUB1273_RS09060	1823066..1823449	-	384	WP_000070811.1	hypothetical protein	-
JMUB1273_RS09065	1824134..1824580	-	447	WP_000747802.1	DUF1433 domain-containing protein	-
JMUB1273_RS09075	1825031..1825126	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1825154..1825211	-	58	-	-	Antitoxin
JMUB1273_RS09080	1825249..1825350	+	102	WP_001791232.1	hypothetical protein	-
JMUB1273_RS09085	1825328..1825510	-	183	Protein_1709	transposase	-
JMUB1273_RS09090	1825698..1826072	-	375	WP_000695818.1	DUF1433 domain-containing protein	-
JMUB1273_RS09095	1826094..1826441	-	348	WP_001566695.1	DUF1433 domain-containing protein	-
JMUB1273_RS09100	1826651..1827094	-	444	WP_000742594.1	DUF1433 domain-containing protein	-
JMUB1273_RS09105	1827742..1828860	-	1119	WP_000072558.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1817512..1845871	28359

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T32421 WP_001801861.1 NZ_AP018922:1825031-1825126 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T32421 NZ_AP018922:1825031-1825126 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT32421 NZ_AP018922:c1825211-1825154 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin