Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1454968..1455556 Replicon chromosome
Accession NZ_AP018907
Organism Blastochloris tepida strain GI

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BLTE_RS06780 Protein ID WP_126398746.1
Coordinates 1455275..1455556 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BLTE_RS06775 Protein ID WP_126398744.1
Coordinates 1454968..1455264 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLTE_RS06740 1450323..1450736 + 414 WP_126398732.1 hypothetical protein -
BLTE_RS18030 1451438..1452202 + 765 WP_160140541.1 tyrosine-type recombinase/integrase -
BLTE_RS06760 1452707..1453510 - 804 WP_126398738.1 enoyl-CoA hydratase/isomerase family protein -
BLTE_RS06765 1453591..1454442 + 852 WP_126398740.1 serine O-acetyltransferase -
BLTE_RS06770 1454480..1454692 + 213 WP_126398742.1 DUF3126 family protein -
BLTE_RS06775 1454968..1455264 - 297 WP_126398744.1 HigA family addiction module antidote protein Antitoxin
BLTE_RS06780 1455275..1455556 - 282 WP_126398746.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BLTE_RS06785 1455713..1456222 + 510 WP_160140542.1 lipocalin family protein -
BLTE_RS06795 1456660..1457265 + 606 WP_126398750.1 hypothetical protein -
BLTE_RS06800 1457578..1458564 - 987 WP_126398752.1 RNA methyltransferase -
BLTE_RS06815 1459706..1460113 - 408 WP_126398754.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(7-82)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10328.87 Da        Isoelectric Point: 9.0463

>T32413 WP_126398746.1 NZ_AP018907:c1455556-1455275 [Blastochloris tepida]
MILNFKDKLTEAVWNGAVGKGFPADLARVAQRKLAMLNAAVTIDALRVPPANRLEALKGDRAGQYAIRVNDQFRVCFVWR
DGNAADVEITDYH

Download         Length: 282 bp

>T32413 NZ_AP018907:c1455556-1455275 [Blastochloris tepida]
ATGATCCTGAATTTCAAGGACAAGCTGACGGAAGCGGTGTGGAATGGCGCCGTCGGCAAGGGCTTCCCGGCGGACCTCGC
GCGGGTGGCGCAACGCAAGCTCGCCATGCTGAACGCCGCCGTCACGATCGATGCTCTCCGCGTTCCGCCCGCCAACCGGC
TGGAAGCCCTGAAAGGGGATCGCGCCGGCCAGTACGCCATTCGCGTGAACGACCAATTCCGCGTGTGCTTCGTCTGGCGC
GACGGCAATGCCGCCGACGTCGAAATCACGGACTACCATTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10842.48 Da        Isoelectric Point: 6.8792

>AT32413 WP_126398744.1 NZ_AP018907:c1455264-1454968 [Blastochloris tepida]
MIGPTPAVHPGEILREEFLLPLGLKPYGLAKSLRVPRTRIERLAREEVPVTADTALRLGRYFGTGPEFWMNLQTAYDIAT
TASNLPDLSEIHPHHAAA

Download         Length: 297 bp

>AT32413 NZ_AP018907:c1455264-1454968 [Blastochloris tepida]
ATGATCGGCCCGACCCCTGCCGTCCATCCGGGGGAAATCCTGCGGGAAGAATTCCTTCTCCCCCTGGGCCTGAAGCCCTA
CGGCCTCGCCAAGTCGCTGCGGGTGCCGCGGACGCGTATCGAGCGCCTGGCGCGTGAGGAGGTGCCCGTTACGGCCGACA
CCGCGTTGCGCCTTGGCCGCTATTTCGGCACCGGCCCGGAGTTCTGGATGAACCTCCAGACCGCCTATGACATTGCGACC
ACCGCGTCGAATCTCCCGGACCTCTCGGAAATCCACCCTCACCACGCCGCTGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References