Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 152816..153238 | Replicon | plasmid pSK1144 |
Accession | NZ_AP018785 | ||
Organism | Escherichia coli strain SK1144 |
Toxin (Protein)
Gene name | hok | Uniprot ID | B1VC78 |
Locus tag | DAECLI1_RS25965 | Protein ID | WP_001302184.1 |
Coordinates | 153080..153238 (+) | Length | 53 a.a. |
Antitoxin (RNA)
Gene name | sok | ||
Locus tag | - | ||
Coordinates | 152816..153015 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DAECLI1_RS25930 | 147993..148463 | - | 471 | WP_024187138.1 | hypothetical protein | - |
DAECLI1_RS25940 | 148765..149292 | + | 528 | WP_000290833.1 | single-stranded DNA-binding protein | - |
DAECLI1_RS25945 | 149349..149582 | + | 234 | WP_000006018.1 | DUF905 domain-containing protein | - |
DAECLI1_RS25950 | 149641..151599 | + | 1959 | WP_001145501.1 | ParB/RepB/Spo0J family partition protein | - |
DAECLI1_RS25955 | 151654..152088 | + | 435 | WP_000845910.1 | conjugation system SOS inhibitor PsiB | - |
DAECLI1_RS25960 | 152085..152804 | + | 720 | WP_001276230.1 | plasmid SOS inhibition protein A | - |
- | 152816..153015 | + | 200 | NuclAT_1 | - | Antitoxin |
- | 152816..153015 | + | 200 | NuclAT_1 | - | Antitoxin |
- | 152816..153015 | + | 200 | NuclAT_1 | - | Antitoxin |
- | 152816..153015 | + | 200 | NuclAT_1 | - | Antitoxin |
DAECLI1_RS25965 | 153080..153238 | + | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | Toxin |
DAECLI1_RS25985 | 154154..154441 | + | 288 | WP_000107526.1 | hypothetical protein | - |
DAECLI1_RS25990 | 154560..155381 | + | 822 | WP_001234489.1 | DUF945 domain-containing protein | - |
DAECLI1_RS25995 | 155678..156280 | - | 603 | WP_001323326.1 | transglycosylase SLT domain-containing protein | - |
DAECLI1_RS26000 | 156611..156994 | + | 384 | WP_001151562.1 | relaxosome protein TraM | - |
DAECLI1_RS26005 | 157188..157874 | + | 687 | WP_000332487.1 | PAS domain-containing protein | - |
DAECLI1_RS26010 | 157968..158195 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Conjugative plasmid | - | senB | 1..169561 | 169561 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 53 a.a. Molecular weight: 6108.35 Da Isoelectric Point: 9.1977
>T32267 WP_001302184.1 NZ_AP018785:153080-153238 [Escherichia coli]
MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK
MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK
Download Length: 159 bp
>T32267 NZ_AP018785:153080-153238 [Escherichia coli]
ATGAAACTACCACGCAGCTCTCTTGTCTGGTGTGTGTTGATCGTGTGTCTCACACTGTTGATATTCACTTATCTGACACG
AAAATCGCTGTGCGAGATTCGTTACAGAGACGGATACAGGGAGGTGGCGGCTTTCATGGCTTACGAATCCGGTAAGTAG
ATGAAACTACCACGCAGCTCTCTTGTCTGGTGTGTGTTGATCGTGTGTCTCACACTGTTGATATTCACTTATCTGACACG
AAAATCGCTGTGCGAGATTCGTTACAGAGACGGATACAGGGAGGTGGCGGCTTTCATGGCTTACGAATCCGGTAAGTAG
Antitoxin
Download Length: 200 bp
>AT32267 NZ_AP018785:152816-153015 [Escherichia coli]
TCACAACGGATTGCCCGTAAACAGCCTGAATGAGCGAGTTATTTTCAGGAAAAGTGAATGTGGTCAGCGTGCTGGTATAT
GGGCTATGATGTGCCCGGCGCTTGAGGTTTTCTGCCTCATGACGTGAAGGTGGTTTGTTACCGTGTTGTGTGGCAGAAGG
ACAAAAGCCCCGTAGTTAATTTTTCATTAACCCACGAGGC
TCACAACGGATTGCCCGTAAACAGCCTGAATGAGCGAGTTATTTTCAGGAAAAGTGAATGTGGTCAGCGTGCTGGTATAT
GGGCTATGATGTGCCCGGCGCTTGAGGTTTTCTGCCTCATGACGTGAAGGTGGTTTGTTACCGTGTTGTGTGGCAGAAGG
ACAAAAGCCCCGTAGTTAATTTTTCATTAACCCACGAGGC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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