Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 1366922..1367535 Replicon chromosome
Accession NZ_AP018738
Organism Ferriphaselus amnicola strain OYT1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OYT1_RS06800 Protein ID WP_062627165.1
Coordinates 1366922..1367245 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OYT1_RS06805 Protein ID WP_197714066.1
Coordinates 1367242..1367535 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OYT1_RS13560 1363103..1363762 - 660 WP_145983680.1 hypothetical protein -
OYT1_RS06775 1363785..1364408 - 624 WP_172588518.1 hypothetical protein -
OYT1_RS06780 1364444..1364866 - 423 WP_062627162.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
OYT1_RS06785 1364863..1365570 - 708 WP_062627163.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
OYT1_RS06790 1365570..1366004 - 435 WP_110818387.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
OYT1_RS06800 1366922..1367245 + 324 WP_062627165.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OYT1_RS06805 1367242..1367535 + 294 WP_197714066.1 helix-turn-helix domain-containing protein Antitoxin
OYT1_RS06810 1367576..1367983 - 408 WP_062627166.1 hypothetical protein -
OYT1_RS06815 1368132..1368350 + 219 WP_062627167.1 hypothetical protein -
OYT1_RS06820 1368375..1368581 + 207 WP_084612029.1 hypothetical protein -
OYT1_RS06825 1368767..1370032 - 1266 WP_062627168.1 RES domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-93)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12196.48 Da        Isoelectric Point: 9.8710

>T32005 WP_062627165.1 NZ_AP018738:1366922-1367245 [Ferriphaselus amnicola]
MDYTITYYSAALQTEIMSLPETLQARYIGLTARMMVYGANLGEPHTKAFGDGLFELRLKGAEGIARVFYCTLVGRQIVML
HCFVKKTQKTPLKERLTAQKRMMEVKL

Download         Length: 324 bp

>T32005 NZ_AP018738:1366922-1367245 [Ferriphaselus amnicola]
ATGGACTACACCATCACCTATTACAGTGCAGCGCTCCAAACGGAGATTATGTCTCTGCCCGAGACGTTACAGGCACGCTA
CATCGGATTGACTGCGAGGATGATGGTATATGGGGCGAATCTCGGCGAACCGCATACCAAAGCCTTTGGGGATGGCTTGT
TCGAGTTGCGCCTCAAAGGAGCGGAAGGCATCGCCCGTGTGTTTTATTGCACGCTGGTCGGTCGCCAGATCGTCATGCTG
CATTGCTTCGTCAAGAAGACGCAGAAAACACCGCTTAAGGAACGCCTGACTGCCCAAAAACGAATGATGGAGGTAAAGCT
ATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10635.37 Da        Isoelectric Point: 10.5509

>AT32005 WP_197714066.1 NZ_AP018738:1367242-1367535 [Ferriphaselus amnicola]
MKTMTHEQMVAKMMGNPAVRAEHERLNREDFAVLDEILAARREAGLTQAQIAERMGTKAPAIARLESALASGKHSPSLST
LRKYAAALGKRVEVHLV

Download         Length: 294 bp

>AT32005 NZ_AP018738:1367242-1367535 [Ferriphaselus amnicola]
ATGAAAACCATGACCCACGAACAAATGGTCGCCAAGATGATGGGAAATCCCGCTGTGCGCGCCGAACATGAGCGACTGAA
CCGCGAAGACTTCGCCGTCTTAGACGAGATCCTTGCCGCTCGGCGCGAGGCGGGTTTAACACAAGCACAGATCGCTGAAC
GCATGGGAACCAAAGCCCCCGCCATCGCCCGCCTCGAAAGTGCGCTGGCTAGCGGCAAGCACTCGCCCAGTCTCAGCACC
TTGCGCAAATACGCGGCTGCATTGGGTAAGCGCGTAGAGGTGCATCTGGTTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References