31973

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 2515605..2516961 Replicon chromosome
Accession NZ_AP018685
Organism Vibrio rumoiensis strain FERM P-14531

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag VRUMOI_RS11495 Protein ID WP_089138388.1
Coordinates 2515915..2516961 (+) Length 349 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag VRUMOI_RS11490 Protein ID WP_089138389.1
Coordinates 2515605..2515931 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VRUMOI_RS11465 2511186..2512166 - 981 WP_089138394.1 substrate-binding domain-containing protein -
VRUMOI_RS11470 2512181..2512999 - 819 WP_089138393.1 DeoR/GlpR family DNA-binding transcription regulator -
VRUMOI_RS11475 2513745..2514032 - 288 WP_089138392.1 hypothetical protein -
VRUMOI_RS11480 2514325..2514606 - 282 WP_089138391.1 hypothetical protein -
VRUMOI_RS11485 2515300..2515620 + 321 WP_089138390.1 helix-turn-helix transcriptional regulator -
VRUMOI_RS11490 2515605..2515931 + 327 WP_089138389.1 HipA N-terminal domain-containing protein Antitoxin
VRUMOI_RS11495 2515915..2516961 + 1047 WP_089138388.1 HipA domain-containing protein Toxin
VRUMOI_RS11500 2517132..2517506 + 375 Protein_2190 transposase -
VRUMOI_RS11505 2517857..2518447 - 591 WP_089138387.1 hypothetical protein -
VRUMOI_RS11510 2518589..2519077 - 489 WP_089138386.1 hypothetical protein -
VRUMOI_RS11515 2519417..2520130 - 714 WP_089138385.1 hypothetical protein -
VRUMOI_RS11520 2520434..2521666 - 1233 WP_110410661.1 Y-family DNA polymerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(60-309)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 349 a.a.        Molecular weight: 39512.94 Da        Isoelectric Point: 5.0506

>T31973 WP_089138388.1 NZ_AP018685:2515915-2516961 [Vibrio rumoiensis]
MNPSNRSLISLDELNEQNREQVEYKKGEIKKLLGSNRFQIQLPFSRAEFVTELPKKQKGMSISGYQPKLSLAINDDHQLG
VAVDKALFILKPSPEEFPHLAENEHATMLVMKFLGFDTPPFGLVRFNDQDGEGELAFMIRRYDRLNAGEEAIHQEQLDAA
MGVREKYGKTEGDAEGYVSYEQACKFLINKVDGSLNFKKELFNRILVAYFLGNNDLHLRNIGLLLPEQENTRLAPIYDYV
SIAPYPGYIANESPLALPLLASEEGDNCNTSGYQSHSTYTGYDFLTFAQNIGLNPKLATKMIKDLCAKQEAILDIYRNSF
MLPEHVEKVAEWIFSRINYLGQLEHVTI

Download         Length: 1047 bp

>T31973 NZ_AP018685:2515915-2516961 [Vibrio rumoiensis]
ATGAATCCGAGCAATAGAAGTCTTATTAGCCTTGATGAGCTCAATGAGCAAAATAGAGAGCAAGTCGAGTATAAAAAAGG
GGAGATCAAAAAACTACTAGGTTCAAATCGATTTCAGATCCAATTACCTTTTTCGCGAGCTGAATTTGTTACGGAGTTAC
CAAAGAAACAAAAAGGGATGAGTATTTCCGGTTATCAACCGAAGCTTTCTCTTGCGATTAATGACGATCATCAGCTAGGG
GTGGCGGTGGATAAGGCTCTATTTATTCTCAAGCCTTCACCAGAAGAATTTCCTCATCTTGCCGAAAACGAACACGCAAC
AATGTTAGTCATGAAATTCCTCGGTTTCGATACACCTCCATTTGGATTAGTTAGGTTCAACGATCAAGACGGCGAAGGTG
AACTCGCCTTTATGATTAGGCGCTATGACCGCTTAAACGCAGGTGAAGAGGCGATCCATCAGGAACAGCTGGATGCCGCA
ATGGGTGTACGGGAGAAGTACGGGAAGACAGAAGGCGATGCCGAGGGATATGTGAGCTACGAGCAAGCCTGTAAGTTCTT
AATAAATAAAGTAGACGGCAGCTTAAACTTTAAAAAAGAACTATTTAACCGAATACTCGTCGCCTACTTTCTCGGTAATA
ATGACCTACACCTTAGAAATATTGGTTTACTGCTACCGGAACAGGAGAACACTCGACTTGCGCCAATCTATGATTACGTG
TCTATAGCGCCTTATCCAGGCTACATCGCAAACGAGAGCCCATTAGCATTACCTCTTCTCGCTAGTGAAGAAGGCGATAA
TTGCAATACCAGTGGCTATCAATCACATAGTACCTACACCGGCTATGACTTTTTAACCTTCGCACAAAATATTGGTCTCA
ACCCTAAACTAGCGACTAAAATGATCAAAGATTTGTGTGCTAAGCAAGAGGCAATTCTCGATATTTACCGTAATAGTTTC
ATGCTGCCAGAGCACGTAGAGAAAGTAGCTGAATGGATATTTAGCAGAATCAACTATTTGGGTCAATTAGAGCATGTTAC
TATTTAA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12321.13 Da        Isoelectric Point: 5.1889

>AT31973 WP_089138389.1 NZ_AP018685:2515605-2515931 [Vibrio rumoiensis]
MDRKVKVLLYGKFCGVLSQNEQGFIFEYEPSYKGRSLSLSMPVADGPFESKELHPFFLSIAPEGWLKKRYSELQKIDEND
PLGMLLSNGKNLLGAVQLLRLEDHESEQ

Download         Length: 327 bp

>AT31973 NZ_AP018685:2515605-2515931 [Vibrio rumoiensis]
ATGGATAGAAAAGTAAAAGTTCTTTTGTACGGTAAGTTTTGCGGTGTATTGTCTCAAAATGAACAAGGTTTTATATTCGA
ATATGAGCCTAGTTATAAAGGCCGTAGCTTATCGCTGAGTATGCCTGTCGCCGATGGGCCATTTGAGAGTAAAGAACTCC
ATCCTTTTTTCCTCAGTATTGCCCCCGAAGGATGGCTAAAGAAGCGCTACTCAGAACTACAAAAAATTGATGAAAACGAT
CCACTAGGTATGCTTTTATCCAATGGCAAAAATTTACTTGGCGCTGTCCAACTGTTGAGGTTAGAAGACCATGAATCCGA
GCAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References