31972

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 2492264..2493624 Replicon chromosome
Accession NZ_AP018685
Organism Vibrio rumoiensis strain FERM P-14531

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag VRUMOI_RS11375 Protein ID WP_197712946.1
Coordinates 2492692..2493624 (+) Length 311 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag VRUMOI_RS11370 Protein ID WP_089138409.1
Coordinates 2492264..2492575 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VRUMOI_RS11350 2487899..2488768 + 870 WP_089139620.1 DMT family transporter -
VRUMOI_RS11355 2489481..2490428 + 948 WP_110410617.1 IS30 family transposase -
VRUMOI_RS11360 2490403..2491596 - 1194 WP_089138411.1 dienelactone hydrolase family protein -
VRUMOI_RS11365 2491959..2492279 + 321 WP_089138410.1 helix-turn-helix transcriptional regulator -
VRUMOI_RS11370 2492264..2492575 + 312 WP_089138409.1 HipA N-terminal domain-containing protein Antitoxin
VRUMOI_RS11375 2492692..2493624 + 933 WP_197712946.1 HipA domain-containing protein Toxin
VRUMOI_RS11380 2493938..2495380 - 1443 WP_089138407.1 IS66 family transposase -
VRUMOI_RS11385 2495758..2496558 + 801 WP_197712947.1 EfeM/EfeO family lipoprotein -
VRUMOI_RS11390 2496563..2497837 + 1275 WP_089138406.1 deferrochelatase/peroxidase EfeB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(21-271)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 311 a.a.        Molecular weight: 35363.31 Da        Isoelectric Point: 4.8726

>T31972 WP_197712946.1 NZ_AP018685:2492692-2493624 [Vibrio rumoiensis]
MRLPFTREEFVNELPKKQKGMSISGYQPKLSLAINDENELGVVEEKALFILKPSPTEFPYLAENEHATMLVMKALGFDLP
PFGLVRFREEDEDSERAFIIRRYDRLKAGEEAIHQEQLDAAMSVSEKYGKIKDDGEGYISYEQACKFLISHVNSSLSFKR
ELFNRVLTAYFLGNNDLHLRNIGILLPEKGAAQLAPIYDYVSIAPYPDYIANETTLALPLLASEEGDNGNTSGYISHCTY
TGFDFLTFAENIGIKPKLAKKWIEELCANTKKIKDIYQNSFMPEAHIVKVTEWIDSRKNYLLQLEHVDID

Download         Length: 933 bp

>T31972 NZ_AP018685:2492692-2493624 [Vibrio rumoiensis]
ATGCGTTTGCCTTTTACACGTGAGGAGTTTGTTAATGAACTGCCCAAAAAACAGAAAGGCATGAGTATTTCTGGTTATCA
ACCAAAATTATCGTTAGCAATTAACGATGAAAATGAGCTCGGAGTTGTAGAAGAGAAGGCTTTGTTTATTCTTAAACCTT
CGCCCACAGAGTTTCCTTATTTAGCGGAAAATGAGCATGCCACTATGTTGGTGATGAAAGCGCTTGGTTTTGATTTACCT
CCGTTTGGTTTGGTTCGCTTTCGTGAAGAGGACGAAGACAGCGAGCGCGCTTTTATTATTAGACGTTATGACCGTTTAAA
AGCAGGCGAAGAAGCGATCCATCAAGAGCAGCTAGATGCGGCCATGAGTGTTAGCGAAAAGTACGGGAAGATAAAAGATG
ATGGTGAGGGTTATATTAGCTACGAGCAGGCCTGCAAATTCTTAATCAGTCATGTAAACAGTAGCTTGTCATTTAAAAGG
GAGCTGTTTAATCGGGTACTAACCGCATATTTCCTTGGTAACAATGATCTCCATTTGCGCAATATCGGCATACTTTTGCC
AGAGAAAGGCGCAGCACAACTCGCGCCTATTTATGATTATGTATCGATAGCTCCTTACCCTGACTACATTGCTAACGAAA
CCACATTAGCACTACCGCTTTTAGCTAGCGAAGAAGGTGATAATGGAAATACGAGCGGCTATATTTCACATTGCACCTAT
ACTGGCTTTGATTTTCTCACGTTTGCTGAAAATATTGGGATTAAGCCAAAGTTAGCTAAAAAATGGATTGAAGAACTTTG
TGCAAATACAAAGAAGATTAAAGACATCTACCAGAATAGTTTCATGCCTGAAGCACATATTGTAAAGGTGACGGAGTGGA
TTGATAGTCGGAAGAACTACTTACTTCAACTTGAACACGTAGACATCGATTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11842.77 Da        Isoelectric Point: 7.1642

>AT31972 WP_089138409.1 NZ_AP018685:2492264-2492575 [Vibrio rumoiensis]
MDRKVKVLLYGKFCGVLTQDVHGFTFEYDASYKGRSLSLSMPLNEKIFESKELHPFFLSLAPEGWLKKRYSELQKIDEND
PLGMLLSNGKNLLGAVQLMRLEE

Download         Length: 312 bp

>AT31972 NZ_AP018685:2492264-2492575 [Vibrio rumoiensis]
ATGGATAGAAAAGTAAAAGTTCTACTGTATGGGAAGTTTTGCGGTGTACTAACCCAAGATGTGCATGGGTTTACCTTTGA
GTATGATGCTTCGTATAAAGGACGAAGCTTGTCACTGAGTATGCCACTAAATGAAAAGATATTTGAGAGCAAAGAGTTAC
ACCCATTCTTTCTTAGCCTTGCGCCAGAAGGTTGGCTGAAAAAGCGCTATTCTGAGTTACAGAAAATTGATGAAAATGAT
CCGCTTGGTATGCTTTTGTCAAATGGCAAAAACTTACTTGGCGCAGTACAACTGATGAGGTTAGAAGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References