Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 352501..353020 Replicon chromosome
Accession NZ_AP018585
Organism Staphylococcus caprae strain JMUB145

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag EL290_RS01520 Protein ID WP_037541722.1
Coordinates 352501..352770 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag EL290_RS01525 Protein ID WP_037541721.1
Coordinates 352763..353020 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL290_RS01500 349412..350170 + 759 WP_002444608.1 esterase family protein -
EL290_RS01505 350252..350563 - 312 WP_002444606.1 SdpI family protein -
EL290_RS01510 350801..351940 + 1140 WP_095323335.1 CapA family protein -
EL290_RS01515 351991..352356 - 366 WP_037541723.1 DUF4870 domain-containing protein -
EL290_RS01520 352501..352770 - 270 WP_037541722.1 Txe/YoeB family addiction module toxin Toxin
EL290_RS01525 352763..353020 - 258 WP_037541721.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EL290_RS01530 353210..354067 + 858 WP_002444596.1 ABC transporter substrate-binding protein -
EL290_RS01535 354181..355821 - 1641 WP_002444595.1 alpha-keto acid decarboxylase family protein -
EL290_RS01540 355993..356439 + 447 WP_002444594.1 MarR family winged helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10552.23 Da        Isoelectric Point: 10.0266

>T31905 WP_037541722.1 NZ_AP018585:c352770-352501 [Staphylococcus caprae]
MSKLNVTFTTQAFKDYQFWQQHNLGNFKKINTLLKSIARDGCIEGIGKPEALKVNYEGYYSRRITIEHRLVYKIKNDSIF
IVSCRFHYL

Download         Length: 270 bp

>T31905 NZ_AP018585:c352770-352501 [Staphylococcus caprae]
ATGAGTAAACTTAATGTGACTTTTACAACTCAAGCATTTAAAGATTATCAATTTTGGCAACAACATAACTTAGGAAATTT
TAAAAAAATTAACACTTTACTTAAAAGTATCGCACGAGATGGTTGCATCGAGGGTATCGGGAAACCGGAAGCGCTAAAAG
TCAATTATGAAGGTTATTATAGTAGGAGAATCACGATTGAACATCGGTTAGTATACAAAATAAAGAATGATTCTATTTTT
ATAGTGTCTTGTAGATTTCATTACCTATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9694.68 Da        Isoelectric Point: 4.1677

>AT31905 WP_037541721.1 NZ_AP018585:c353020-352763 [Staphylococcus caprae]
MPSINYSNARQNFKELISKVNEDSVTYTITTKEDKNAVILAEKDYNAILETMYLQSNPANVSHLNKSIQELNQNDTITVE
IDDNE

Download         Length: 258 bp

>AT31905 NZ_AP018585:c353020-352763 [Staphylococcus caprae]
ATGCCATCCATAAATTATTCCAATGCACGTCAAAATTTTAAAGAACTGATTTCTAAAGTAAACGAAGACAGTGTAACTTA
CACAATTACAACGAAAGAAGATAAGAATGCTGTCATTCTAGCTGAGAAAGATTACAATGCAATTCTAGAAACGATGTATC
TTCAGTCAAATCCGGCTAATGTGTCTCACCTGAACAAATCCATTCAAGAATTAAACCAAAACGATACGATTACAGTTGAG
ATTGATGATAATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References