Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 352501..353020 Replicon chromosome
Accession NZ_AP018585
Organism Staphylococcus caprae strain JMUB145

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag EL290_RS01520 Protein ID WP_037541722.1
Coordinates 352501..352770 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag EL290_RS01525 Protein ID WP_037541721.1
Coordinates 352763..353020 (-) Length 86 a.a.

Genomic Context

EL290_RS01500EL290_RS01510EL290_RS01530EL290_RS01540EL290_RS01505EL290_RS01515EL290_RS01520EL290_RS01525EL290_RS01535
Location: 349412..350170 (759 bp)
Type: Others
Protein ID: WP_002444608.1
Location: 350801..351940 (1140 bp)
Type: Others
Protein ID: WP_095323335.1
Location: 353210..354067 (858 bp)
Type: Others
Protein ID: WP_002444596.1
Location: 355993..356439 (447 bp)
Type: Others
Protein ID: WP_002444594.1
Location: 350252..350563 (312 bp)
Type: Others
Protein ID: WP_002444606.1
Location: 351991..352356 (366 bp)
Type: Others
Protein ID: WP_037541723.1
Location: 352501..352770 (270 bp)
Type: Toxin
Protein ID: WP_037541722.1
Location: 352763..353020 (258 bp)
Type: Antitoxin
Protein ID: WP_037541721.1
Location: 354181..355821 (1641 bp)
Type: Others
Protein ID: WP_002444595.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EL290_RS01500349412..350170+759WP_002444608.1esterase family protein-
EL290_RS01505350252..350563-312WP_002444606.1SdpI family protein-
EL290_RS01510350801..351940+1140WP_095323335.1CapA family protein-
EL290_RS01515351991..352356-366WP_037541723.1DUF4870 domain-containing protein-
EL290_RS01520352501..352770-270WP_037541722.1Txe/YoeB family addiction module toxinToxin
EL290_RS01525352763..353020-258WP_037541721.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
EL290_RS01530353210..354067+858WP_002444596.1ABC transporter substrate-binding protein-
EL290_RS01535354181..355821-1641WP_002444595.1alpha-keto acid decarboxylase family protein-
EL290_RS01540355993..356439+447WP_002444594.1MarR family winged helix-turn-helix transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10552.23 Da        Isoelectric Point: 10.0266

>T31905 WP_037541722.1 NZ_AP018585:c352770-352501 [Staphylococcus caprae]
MSKLNVTFTTQAFKDYQFWQQHNLGNFKKINTLLKSIARDGCIEGIGKPEALKVNYEGYYSRRITIEHRLVYKIKNDSIF
IVSCRFHYL

Download         Length: 270 bp

>T31905 NZ_AP018585:c352770-352501 [Staphylococcus caprae]
ATGAGTAAACTTAATGTGACTTTTACAACTCAAGCATTTAAAGATTATCAATTTTGGCAACAACATAACTTAGGAAATTT
TAAAAAAATTAACACTTTACTTAAAAGTATCGCACGAGATGGTTGCATCGAGGGTATCGGGAAACCGGAAGCGCTAAAAG
TCAATTATGAAGGTTATTATAGTAGGAGAATCACGATTGAACATCGGTTAGTATACAAAATAAAGAATGATTCTATTTTT
ATAGTGTCTTGTAGATTTCATTACCTATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9694.68 Da        Isoelectric Point: 4.1677

>AT31905 WP_037541721.1 NZ_AP018585:c353020-352763 [Staphylococcus caprae]
MPSINYSNARQNFKELISKVNEDSVTYTITTKEDKNAVILAEKDYNAILETMYLQSNPANVSHLNKSIQELNQNDTITVE
IDDNE

Download         Length: 258 bp

>AT31905 NZ_AP018585:c353020-352763 [Staphylococcus caprae]
ATGCCATCCATAAATTATTCCAATGCACGTCAAAATTTTAAAGAACTGATTTCTAAAGTAAACGAAGACAGTGTAACTTA
CACAATTACAACGAAAGAAGATAAGAATGCTGTCATTCTAGCTGAGAAAGATTACAATGCAATTCTAGAAACGATGTATC
TTCAGTCAAATCCGGCTAATGTGTCTCACCTGAACAAATCCATTCAAGAATTAAACCAAAACGATACGATTACAGTTGAG
ATTGATGATAATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References