Detailed information of TA system TA031903

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2437217..2437401
• Replicon: chromosome
• Accession: NZ_AP018562
• Organism: Staphylococcus argenteus strain 58113

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: SA58113_RS12080
• Protein ID: WP_000482653.1
• Coordinates: 2437294..2437401 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2437217..2437277 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SA58113_RS12065	2433069..2434802	-	1734	WP_031787186.1	ABC transporter ATP-binding protein/permease	-
SA58113_RS12070	2434827..2436590	-	1764	WP_031787187.1	ABC transporter ATP-binding protein/permease	-
-	2437217..2437277	+	61	-	-	Antitoxin
SA58113_RS12080	2437294..2437401	-	108	WP_000482653.1	type I toxin-antitoxin system Fst family toxin	Toxin
SA58113_RS12085	2437535..2437921	-	387	WP_000779346.1	flippase GtxA	-
SA58113_RS12090	2438189..2439331	+	1143	WP_031787188.1	glycerate kinase	-
SA58113_RS12095	2439390..2440049	+	660	WP_000831306.1	membrane protein	-
SA58113_RS12100	2440234..2441445	+	1212	WP_031787189.1	multidrug effflux MFS transporter	-
SA58113_RS12105	2441561..2442040	-	480	WP_031787190.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4025.81 Da
• Isoelectric Point: 11.0582

>T31903 WP_000482653.1 NZ_AP018562:c2437401-2437294 [Staphylococcus argenteus]
MFNLLINIMTTAISGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T31903 NZ_AP018562:c2437401-2437294 [Staphylococcus argenteus]
ATGTTCAATTTATTGATTAACATCATGACTACAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT31903 NZ_AP018562:2437217-2437277 [Staphylococcus argenteus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin