Detailed information of TA system TA031896

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprG2-SprA2AS/-
• Location: 1032157..1032374
• Replicon: chromosome
• Accession: NZ_AP018562
• Organism: Staphylococcus argenteus strain 58113

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: SA58113_RS05135
• Protein ID: WP_031787354.1
• Coordinates: 1032157..1032264 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1032259..1032374 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SA58113_RS05110	1028836..1029405	-	570	WP_000287261.1	competence protein ComK	-
SA58113_RS05115	1029615..1029833	+	219	WP_000876831.1	IDEAL domain-containing protein	-
SA58113_RS05120	1029914..1030900	-	987	WP_000668810.1	lipoate--protein ligase	-
SA58113_RS05125	1031095..1031271	+	177	WP_000214898.1	YkvS family protein	-
SA58113_RS05130	1031286..1031888	+	603	WP_031787353.1	CPBP family intramembrane metalloprotease	-
SA58113_RS05135	1032157..1032264	+	108	WP_031787354.1	putative holin-like toxin	Toxin
-	1032259..1032374	-	116	-	-	Antitoxin
SA58113_RS05140	1032899..1033180	+	282	Protein_979	lactococcin 972 family bacteriocin	-
SA58113_RS05145	1033224..1035188	+	1965	WP_031787355.1	bacteriocin-associated integral membrane family protein	-
SA58113_RS05150	1035191..1035511	+	321	WP_031787356.1	YxeA family protein	-
SA58113_RS05155	1035508..1036149	+	642	WP_031787357.1	ABC transporter ATP-binding protein	-
SA58113_RS05160	1036237..1036497	-	261	WP_169929182.1	hypothetical protein	-
SA58113_RS05165	1036812..1037099	+	288	WP_000410715.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3815.72 Da
• Isoelectric Point: 10.8004

>T31896 WP_031787354.1 NZ_AP018562:1032157-1032264 [Staphylococcus argenteus]
VISIANALHLMLSFGMFIVTFIGIVVAIININNKK

Nucleotide

• Length: 108 bp

>T31896 NZ_AP018562:1032157-1032264 [Staphylococcus argenteus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTAACTTTCATTGGTATAGTAGTCGC
AATAATTAATATAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 116 bp

>AT31896 NZ_AP018562:c1032374-1032259 [Staphylococcus argenteus]
GTAAAAAGACGACATGCAGGAACATGTCGCCTATTGAGCCCGTTAAAAAGACGGTGACTAAATGAGATTTTCTTTAACCA
TCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin