Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2774877..2775194 | Replicon | chromosome |
Accession | NZ_AP018538 | ||
Organism | Enterococcus faecalis strain KUB3006 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | E2Z0W4 |
Locus tag | EL240_RS14050 | Protein ID | WP_002381035.1 |
Coordinates | 2775051..2775194 (+) | Length | 48 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2774877..2774940 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EL240_RS14025 | 2770767..2771399 | - | 633 | WP_002358972.1 | RloB family protein | - |
EL240_RS14030 | 2771408..2772703 | - | 1296 | WP_002371641.1 | AAA family ATPase | - |
EL240_RS14045 | 2773165..2774781 | + | 1617 | WP_002406969.1 | phosphatase PAP2/LCP family protein | - |
- | 2774877..2774940 | - | 64 | - | - | Antitoxin |
EL240_RS14050 | 2775051..2775194 | + | 144 | WP_002381035.1 | putative holin-like toxin | Toxin |
EL240_RS14055 | 2775389..2778388 | - | 3000 | WP_033786695.1 | WxL domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 48 a.a. Molecular weight: 5202.20 Da Isoelectric Point: 10.0041
>T31850 WP_002381035.1 NZ_AP018538:2775051-2775194 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKENNKK
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKENNKK
Download Length: 144 bp
>T31850 NZ_AP018538:2775051-2775194 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTAAAAGAAAACAATAAAAAATAA
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTAAAAGAAAACAATAAAAAATAA
Antitoxin
Download Length: 64 bp
>AT31850 NZ_AP018538:c2774940-2774877 [Enterococcus faecalis]
TTGTGCTATAATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTGATGTAGAGCCGTT
TTGTGCTATAATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTGATGTAGAGCCGTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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