Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ldrD-rdlD/Ldr(toxin) |
Location | 1609084..1609298 | Replicon | chromosome |
Accession | NZ_AP018488 | ||
Organism | Escherichia coli O157:H7 strain PV15-279 |
Toxin (Protein)
Gene name | ldrD | Uniprot ID | J7R083 |
Locus tag | ECpv15279_RS08010 | Protein ID | WP_000170963.1 |
Coordinates | 1609084..1609191 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | rdlD | ||
Locus tag | - | ||
Coordinates | 1609239..1609298 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ECpv15279_RS07980 | 1604393..1605475 | + | 1083 | WP_000804726.1 | peptide chain release factor 1 | - |
ECpv15279_RS07985 | 1605475..1606308 | + | 834 | WP_000456464.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
ECpv15279_RS07990 | 1606305..1606697 | + | 393 | WP_000200379.1 | invasion regulator SirB2 | - |
ECpv15279_RS07995 | 1606701..1607510 | + | 810 | WP_001257044.1 | invasion regulator SirB1 | - |
ECpv15279_RS08000 | 1607546..1608400 | + | 855 | WP_000811065.1 | 3-deoxy-8-phosphooctulonate synthase | - |
ECpv15279_RS08005 | 1608548..1608655 | - | 108 | WP_000170954.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
- | 1608708..1608769 | + | 62 | NuclAT_24 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_24 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_24 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_24 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_26 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_26 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_26 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_26 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_28 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_28 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_28 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_28 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_30 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_30 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_30 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_30 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_32 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_32 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_32 | - | - |
- | 1608708..1608769 | + | 62 | NuclAT_32 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_17 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_17 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_17 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_17 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_18 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_18 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_18 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_18 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_19 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_19 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_19 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_19 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_20 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_20 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_20 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_20 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_22 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_22 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_22 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_22 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_23 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_23 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_23 | - | - |
- | 1608708..1608770 | + | 63 | NuclAT_23 | - | - |
ECpv15279_RS08010 | 1609084..1609191 | - | 108 | WP_000170963.1 | small toxic polypeptide LdrB | Toxin |
- | 1609239..1609298 | + | 60 | NuclAT_25 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_25 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_25 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_25 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_27 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_27 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_27 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_27 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_29 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_29 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_29 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_29 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_31 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_31 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_31 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_31 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_33 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_33 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_33 | - | Antitoxin |
- | 1609239..1609298 | + | 60 | NuclAT_33 | - | Antitoxin |
ECpv15279_RS08015 | 1609590..1610690 | - | 1101 | WP_001301956.1 | sodium-potassium/proton antiporter ChaA | - |
ECpv15279_RS08020 | 1610960..1611190 | + | 231 | WP_001146444.1 | putative cation transport regulator ChaB | - |
ECpv15279_RS08025 | 1611351..1612046 | + | 696 | WP_001301489.1 | glutathione-specific gamma-glutamylcyclotransferase | - |
ECpv15279_RS08030 | 1612090..1612443 | - | 354 | WP_001169669.1 | DsrE/F sulfur relay family protein YchN | - |
ECpv15279_RS08035 | 1612629..1614023 | + | 1395 | WP_000086192.1 | inverse autotransporter invasin YchO | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 3971.74 Da Isoelectric Point: 11.4779
>T31803 WP_000170963.1 NZ_AP018488:c1609191-1609084 [Escherichia coli O157:H7]
MTLAQFAMTFWHDLAAPILAGIITAAIVGWWRNRK
MTLAQFAMTFWHDLAAPILAGIITAAIVGWWRNRK
Download Length: 108 bp
>T31803 NZ_AP018488:c1609191-1609084 [Escherichia coli O157:H7]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 60 bp
>AT31803 NZ_AP018488:1609239-1609298 [Escherichia coli O157:H7]
GTCTGGTTTCAAGATTAGCCCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
GTCTGGTTTCAAGATTAGCCCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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