Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2486941..2487125 Replicon chromosome
Accession NZ_AP018349
Organism Staphylococcus aureus strain GN1

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag D8S83_RS12760 Protein ID WP_000482647.1
Coordinates 2487018..2487125 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2486941..2487001 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8S83_RS12740 2482451..2482618 - 168 WP_001789205.1 hypothetical protein -
D8S83_RS12750 2482849..2484582 - 1734 WP_020977552.1 ABC transporter ATP-binding protein/permease -
D8S83_RS12755 2484607..2486370 - 1764 WP_001064822.1 ABC transporter ATP-binding protein/permease -
D8S83_RS14420 2486824..2486991 - 168 WP_000301893.1 hypothetical protein -
- 2486941..2487001 + 61 - - Antitoxin
D8S83_RS12760 2487018..2487125 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
D8S83_RS12765 2487259..2487645 - 387 WP_000779353.1 flippase GtxA -
D8S83_RS12770 2487913..2489055 + 1143 WP_001176863.1 glycerate kinase -
D8S83_RS12775 2489115..2489774 + 660 WP_000831298.1 membrane protein -
D8S83_RS12780 2489957..2491168 + 1212 WP_001191921.1 multidrug effflux MFS transporter -
D8S83_RS12785 2491291..2491764 - 474 WP_020977553.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T31763 WP_000482647.1 NZ_AP018349:c2487125-2487018 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T31763 NZ_AP018349:c2487125-2487018 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT31763 NZ_AP018349:2486941-2487001 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References