Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2282105..2282322 Replicon chromosome
Accession NZ_AP018349
Organism Staphylococcus aureus strain GN1

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag D8S83_RS11645 Protein ID WP_001802298.1
Coordinates 2282218..2282322 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2282105..2282160 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8S83_RS11625 2278238..2278903 - 666 WP_001024095.1 SDR family oxidoreductase -
D8S83_RS11630 2279055..2279375 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
D8S83_RS11635 2279377..2280354 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
D8S83_RS11640 2280620..2281711 + 1092 WP_020977458.1 hypothetical protein -
- 2282105..2282160 + 56 - - Antitoxin
D8S83_RS11645 2282218..2282322 - 105 WP_001802298.1 hypothetical protein Toxin
D8S83_RS14340 2282483..2282986 - 504 Protein_2159 recombinase family protein -
D8S83_RS11655 2283034..2284326 + 1293 WP_020977460.1 IS21 family transposase -
D8S83_RS11660 2284319..2285080 + 762 WP_001066124.1 IS21-like element helper ATPase IstB -
D8S83_RS14400 2285216..2286352 - 1137 Protein_2162 SAP domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2284319..2285080 761


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T31760 WP_001802298.1 NZ_AP018349:c2282322-2282218 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T31760 NZ_AP018349:c2282322-2282218 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT31760 NZ_AP018349:2282105-2282160 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References