Detailed information of TA system TA031754

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1971053..1971233
• Replicon: chromosome
• Accession: NZ_AP018349
• Organism: Staphylococcus aureus strain GN1

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: D8S83_RS09810
• Protein ID: WP_001801861.1
• Coordinates: 1971053..1971148 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1971176..1971233 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D8S83_RS09765	1966517..1967515	+	999	WP_120173197.1	DUF4352 domain-containing protein	-
D8S83_RS09770	1967591..1968217	+	627	WP_000669045.1	hypothetical protein	-
D8S83_RS09775	1968258..1968599	+	342	WP_000627534.1	DUF3969 family protein	-
D8S83_RS09780	1968700..1969272	+	573	WP_000414218.1	hypothetical protein	-
D8S83_RS09785	1969602..1969787	-	186	WP_000809860.1	hypothetical protein	-
D8S83_RS09790	1969789..1969965	-	177	WP_000375478.1	hypothetical protein	-
D8S83_RS09795	1969976..1970265	-	290	Protein_1850	hypothetical protein	-
D8S83_RS09800	1970433..1970666	-	234	Protein_1851	IS3 family transposase	-
D8S83_RS09805	1970672..1970908	-	237	WP_000251969.1	IS3 family transposase	-
D8S83_RS09810	1971053..1971148	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1971176..1971233	-	58	-	-	Antitoxin
D8S83_RS09820	1972089..1972531	-	443	Protein_1854	DUF1433 domain-containing protein	-
D8S83_RS09825	1972531..1972974	-	444	WP_000731420.1	DUF1433 domain-containing protein	-
D8S83_RS09830	1972974..1973417	-	444	WP_000747798.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1970672..1970908	236

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T31754 WP_001801861.1 NZ_AP018349:1971053-1971148 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T31754 NZ_AP018349:1971053-1971148 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT31754 NZ_AP018349:c1971233-1971176 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin