Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 9117857..9118701 Replicon chromosome
Accession NZ_AP018255
Organism Calothrix sp. NIES-4071

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag CDC41_RS40155 Protein ID WP_096691903.1
Coordinates 9117857..9118366 (-) Length 170 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag CDC41_RS40160 Protein ID WP_096691904.1
Coordinates 9118369..9118701 (-) Length 111 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDC41_RS40135 9114403..9114663 + 261 WP_096691899.1 hypothetical protein -
CDC41_RS40140 9114716..9115627 - 912 WP_096691900.1 DMT family transporter -
CDC41_RS40145 9115720..9116892 - 1173 WP_096691901.1 GNAT family N-acetyltransferase -
CDC41_RS40150 9117451..9117768 - 318 WP_096691902.1 hypothetical protein -
CDC41_RS40155 9117857..9118366 - 510 WP_096691903.1 type II toxin-antitoxin system YhaV family toxin Toxin
CDC41_RS40160 9118369..9118701 - 333 WP_096691904.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
CDC41_RS40165 9119554..9121773 - 2220 WP_096691905.1 alpha-1,4 polygalactosaminidase -
CDC41_RS40170 9121888..9123063 + 1176 WP_096691906.1 pentapeptide repeat-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(14-150)

Antitoxin

PrlF antitoxin

(10-108)


Sequences

Toxin        


Download         Length: 170 a.a.        Molecular weight: 20437.25 Da        Isoelectric Point: 9.0582

>T31737 WP_096691903.1 NZ_AP018255:c9118366-9117857 [Calothrix sp. NIES-4071]
MSTSQPLVINGWSIFAHPLFLDELEELLNSVELLRQNDPQNYHKKNTTKRLAAIIKLVFEVIPTEPTRNEYRQGATLGDK
YKHWFRAKFFQQYRLFFRYHQESRIIIFVWVNDEKSKRAYDSKTDAYRVFKKMLQNDYPPDDWDILLKQAEAELNRLQKS
YEKLKEDEQ

Download         Length: 510 bp

>T31737 NZ_AP018255:c9118366-9117857 [Calothrix sp. NIES-4071]
TTGTCTACAAGTCAACCATTAGTAATTAATGGGTGGAGTATTTTTGCCCATCCGCTTTTTCTTGACGAACTTGAGGAGCT
TTTGAATTCTGTTGAACTTCTGCGTCAAAACGACCCTCAAAATTACCATAAAAAAAATACTACAAAACGTTTAGCCGCCA
TCATTAAACTTGTATTTGAAGTTATTCCTACTGAACCTACACGTAACGAGTATCGTCAAGGTGCGACTCTAGGCGATAAG
TATAAACATTGGTTCCGAGCCAAATTTTTTCAACAATATAGACTGTTCTTTAGGTATCACCAAGAAAGTAGGATAATTAT
ATTCGTTTGGGTCAATGATGAAAAATCTAAGCGAGCTTATGACAGTAAGACTGACGCTTACCGAGTCTTTAAAAAAATGC
TTCAAAATGACTACCCTCCGGATGATTGGGATATTCTCCTTAAACAAGCAGAAGCTGAACTTAACCGTTTGCAAAAAAGC
TACGAGAAGCTGAAAGAAGACGAGCAATAA

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 12446.93 Da        Isoelectric Point: 4.2864

>AT31737 WP_096691904.1 NZ_AP018255:c9118701-9118369 [Calothrix sp. NIES-4071]
MAKDFTFQAESTLTDRYQTTIPESVRKALGLNKRDKIHYAIQPNGQVIISNADDVENDPVLGEFLDFLAKDIKNNPQRIK
PITSDLLRRAQSLVADVEFDIDVPLSDEDE

Download         Length: 333 bp

>AT31737 NZ_AP018255:c9118701-9118369 [Calothrix sp. NIES-4071]
ATGGCTAAAGATTTTACTTTTCAAGCAGAATCCACTCTTACTGACCGATACCAAACCACAATTCCTGAAAGTGTGCGAAA
AGCCTTGGGCTTAAATAAGCGCGATAAAATTCATTACGCAATTCAGCCAAATGGTCAAGTCATTATTTCAAATGCTGACG
ATGTGGAAAATGACCCAGTGCTTGGAGAGTTTTTGGATTTTCTTGCCAAAGATATCAAAAATAATCCTCAGCGAATTAAA
CCAATCACTTCTGATTTGCTCAGACGTGCCCAGTCCTTAGTGGCTGATGTTGAGTTTGATATCGATGTACCCTTGTCTGA
TGAGGATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References