Detailed information of TA system TA031702

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 1502295..1502995
• Replicon: chromosome
• Accession: NZ_AP018112
• Organism: Burkholderia stabilis strain FERMP-21014

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: BSFP_RS23945
• Protein ID: WP_096474328.1
• Coordinates: 1502699..1502995 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: A0A0G3X002
• Locus tag: BSFP_RS23940
• Protein ID: WP_047903228.1
• Coordinates: 1502295..1502696 (-)
• Length: 134 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BSFP_RS23920	1497961..1499313	-	1353	WP_096474324.1	LLM class flavin-dependent oxidoreductase	-
BSFP_RS23925	1499321..1500370	-	1050	WP_096474325.1	LLM class flavin-dependent oxidoreductase	-
BSFP_RS23930	1500423..1501364	-	942	WP_096474326.1	ABC transporter substrate-binding protein	-
BSFP_RS23935	1501419..1501979	-	561	WP_096474327.1	GNAT family N-acetyltransferase	-
BSFP_RS23940	1502295..1502696	-	402	WP_047903228.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
BSFP_RS23945	1502699..1502995	-	297	WP_096474328.1	type II toxin-antitoxin system MqsR family toxin	Toxin
BSFP_RS23950	1503104..1504138	-	1035	WP_096474329.1	succinylglutamate desuccinylase/aspartoacylase family protein	-
BSFP_RS23960	1504411..1504686	-	276	WP_096474331.1	hypothetical protein	-
BSFP_RS23965	1504945..1506495	-	1551	WP_096474332.1	sensor domain-containing diguanylate cyclase	-
BSFP_RS35890	1506622..1506938	+	317	Protein_1344	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (5-97)

Antitoxin

• Zinc finger, MqsA-type (3-46)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11281.17 Da
• Isoelectric Point: 8.9573

>T31702 WP_096474328.1 NZ_AP018112:c1502995-1502699 [Burkholderia stabilis]
MEKRRPHCKLPLVKALVESGKVRLTTSAVFGARQLGFTEREALDVVMSLTDLDFHKSMTTYADHTIWQDVYRPLTVRGDV
YLKLTVIDEVLIVSFKER

Nucleotide

• Length: 297 bp

>T31702 NZ_AP018112:c1502995-1502699 [Burkholderia stabilis]
ATGGAAAAGAGAAGGCCTCATTGCAAGCTGCCCCTCGTCAAGGCGCTGGTCGAATCCGGCAAGGTCCGGTTGACCACGAG
CGCGGTATTCGGTGCCCGGCAACTGGGTTTCACGGAAAGGGAGGCGCTCGATGTCGTGATGTCGCTGACCGACCTCGACT
TCCACAAGAGCATGACGACGTACGCCGACCACACGATCTGGCAGGACGTCTACCGGCCGTTGACGGTGCGTGGCGACGTG
TACCTGAAATTGACGGTGATCGACGAGGTGCTGATCGTGTCTTTCAAGGAGCGATGA

Antitoxin

Protein

• Length: 134 a.a.
• Molecular weight: 14619.91 Da
• Isoelectric Point: 8.8304

>AT31702 WP_047903228.1 NZ_AP018112:c1502696-1502295 [Burkholderia stabilis]
MKCPACGAAKLVRDTRDIPYTYKGRSTVVRDITGDFCPACGESVLDLDEATRLGEAIAEFNKQVNATIVDPKYIAKVRKK
LRLDQREAAELFGGGVNAFSRYETGKTNPPLALVKLLKILDRHPDLLAEVRAA

Nucleotide

• Length: 402 bp

>AT31702 NZ_AP018112:c1502696-1502295 [Burkholderia stabilis]
ATGAAGTGTCCTGCATGCGGTGCCGCCAAGCTGGTCCGCGACACGCGAGACATCCCTTATACCTACAAGGGCCGGTCGAC
TGTCGTCCGCGATATCACCGGCGATTTCTGCCCGGCCTGCGGGGAATCCGTACTGGATCTCGACGAGGCGACCCGTCTCG
GCGAAGCGATCGCCGAGTTCAACAAGCAGGTGAACGCAACCATCGTCGACCCGAAGTACATCGCGAAGGTGCGCAAGAAG
CTGAGGCTGGATCAGCGCGAGGCGGCCGAGCTCTTCGGCGGTGGCGTCAACGCGTTCTCCCGTTACGAGACAGGCAAGAC
GAATCCGCCGCTTGCCCTCGTGAAATTGCTGAAAATCCTGGATCGTCACCCCGATCTACTCGCCGAAGTCCGAGCGGCAT
AG

Structures

Antitoxin

• AlphaFold DB: A0A0G3X002