Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 2225622..2226316 Replicon chromosome
Accession NZ_AP018052
Organism Thiohalobacter thiocyanaticus strain FOKN1

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag CFK21_RS10340 Protein ID WP_096366582.1
Coordinates 2225622..2226017 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag CFK21_RS10345 Protein ID WP_096367583.1
Coordinates 2226017..2226316 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFK21_RS10330 2221038..2224520 + 3483 WP_096366580.1 transcription-repair coupling factor -
CFK21_RS10335 2224654..2225397 + 744 WP_096366581.1 peptidoglycan binding protein CsiV -
CFK21_RS10340 2225622..2226017 - 396 WP_096366582.1 type II toxin-antitoxin system YafO family toxin Toxin
CFK21_RS10345 2226017..2226316 - 300 WP_096367583.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
CFK21_RS15255 2226553..2226996 - 444 WP_157745607.1 VPLPA-CTERM sorting domain-containing protein -
CFK21_RS10350 2227427..2227702 - 276 WP_096366583.1 GIY-YIG nuclease family protein -
CFK21_RS10355 2227897..2228145 - 249 WP_096366584.1 BrnA antitoxin family protein -
CFK21_RS10360 2228138..2228422 - 285 WP_096366585.1 BrnT family toxin -
CFK21_RS10365 2228525..2230093 - 1569 WP_096366586.1 bifunctional GNAT family N-acetyltransferase/carbon-nitrogen hydrolase family protein -
CFK21_RS10370 2230103..2230567 - 465 WP_096366587.1 peroxiredoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(26-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 15532.71 Da        Isoelectric Point: 9.0446

>T31690 WP_096366582.1 NZ_AP018052:c2226017-2225622 [Thiohalobacter thiocyanaticus]
MRVFKSRLLQRQLSQSELNQLVADFKQYKETGIPASYFGRDIPYDHPHTLPSVRSEQIMHLHLAEETRQWTKQQPQYNRT
SDHHLVYCQGFFDLNCFLLMAILRPDAHHQARDNTIMRNLATMAAKFRAEF

Download         Length: 396 bp

>T31690 NZ_AP018052:c2226017-2225622 [Thiohalobacter thiocyanaticus]
ATGCGGGTTTTCAAGAGTCGGCTGCTTCAGAGGCAACTCAGTCAGTCTGAATTGAATCAACTTGTAGCTGATTTCAAGCA
GTACAAGGAAACGGGTATCCCTGCGAGTTATTTTGGTCGGGATATCCCATACGATCATCCGCACACTCTGCCTTCCGTTC
GCAGCGAGCAAATTATGCATTTGCATCTGGCGGAAGAAACTCGACAATGGACCAAGCAACAACCGCAGTACAATCGCACC
AGCGATCATCACTTGGTCTACTGTCAGGGATTCTTTGACCTTAATTGTTTTTTATTGATGGCGATCCTGAGGCCGGACGC
GCATCACCAGGCGCGCGATAACACCATCATGCGTAATCTCGCTACTATGGCTGCGAAATTTCGCGCGGAATTCTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11173.43 Da        Isoelectric Point: 4.4118

>AT31690 WP_096367583.1 NZ_AP018052:c2226316-2226017 [Thiohalobacter thiocyanaticus]
MSVQKILADETVSITEFRKRPQAYFTDHAIAVLSNNRTAGYILGAEVYETLLSVLQQSQQFDSFEGRFRPTAARLREIAE
QGEKLLEQASEEDLGSFSE

Download         Length: 300 bp

>AT31690 NZ_AP018052:c2226316-2226017 [Thiohalobacter thiocyanaticus]
ATGAGCGTACAAAAGATTCTTGCTGATGAGACGGTGTCAATCACCGAGTTTCGCAAAAGACCTCAGGCGTACTTCACTGA
TCATGCAATTGCCGTGTTATCCAACAATCGCACGGCAGGTTATATTCTCGGCGCCGAGGTCTATGAAACACTGCTGAGTG
TCTTACAGCAAAGTCAGCAATTCGATTCATTCGAGGGGCGTTTCCGGCCAACTGCTGCGCGGTTGAGAGAAATCGCGGAA
CAAGGGGAAAAACTACTGGAACAAGCCAGTGAAGAAGATTTAGGCTCCTTCTCTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References