Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2425831..2426015 Replicon chromosome
Accession NZ_AP017922
Organism Staphylococcus aureus strain JP02758

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag JP49775_RS12215 Protein ID WP_000482647.1
Coordinates 2425908..2426015 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2425831..2425891 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JP49775_RS12200 2421274..2421452 - 179 Protein_2310 hypothetical protein -
JP49775_RS12205 2421683..2423416 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
JP49775_RS12210 2423441..2425204 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 2425831..2425891 + 61 - - Antitoxin
JP49775_RS12215 2425908..2426015 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
JP49775_RS12220 2426149..2426535 - 387 WP_000779353.1 flippase GtxA -
JP49775_RS12225 2426803..2427945 + 1143 WP_029550219.1 glycerate kinase -
JP49775_RS12230 2428005..2428664 + 660 WP_000831300.1 hypothetical protein -
JP49775_RS12235 2428852..2430063 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
JP49775_RS12240 2430186..2430659 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T31433 WP_000482647.1 NZ_AP017922:c2426015-2425908 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T31433 NZ_AP017922:c2426015-2425908 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT31433 NZ_AP017922:2425831-2425891 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References