Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2135693..2135909 Replicon chromosome
Accession NZ_AP017922
Organism Staphylococcus aureus strain JP02758

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag JP49775_RS10710 Protein ID WP_001802298.1
Coordinates 2135805..2135909 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2135693..2135748 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JP49775_RS10690 2131830..2132495 - 666 WP_001024099.1 SDR family oxidoreductase -
JP49775_RS10695 2132647..2132967 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
JP49775_RS10700 2132969..2133949 + 981 WP_029550399.1 CDF family zinc efflux transporter CzrB -
JP49775_RS10705 2134215..2135306 + 1092 WP_029550400.1 hypothetical protein -
- 2135693..2135748 + 56 - - Antitoxin
JP49775_RS10710 2135805..2135909 - 105 WP_001802298.1 hypothetical protein Toxin
JP49775_RS10720 2136589..2136747 + 159 WP_001792784.1 hypothetical protein -
JP49775_RS10725 2137183..2137275 + 93 WP_001794441.1 hypothetical protein -
JP49775_RS10730 2137405..2138262 - 858 WP_029550401.1 Cof-type HAD-IIB family hydrolase -
JP49775_RS10735 2138330..2139112 - 783 WP_029550402.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF1474

(1-98)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T31431 WP_001802298.1 NZ_AP017922:c2135909-2135805 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T31431 NZ_AP017922:c2135909-2135805 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT31431 NZ_AP017922:2135693-2135748 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References