Detailed information of TA system TA031423

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 963197..963446
• Replicon: chromosome
• Accession: NZ_AP017922
• Organism: Staphylococcus aureus strain JP02758

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: JP49775_RS04615
• Protein ID: WP_000623369.1
• Coordinates: 963197..963304 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	963299..963446 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JP49775_RS04590	959871..960440	-	570	WP_000287265.1	competence protein ComK	-
JP49775_RS04595	960650..960868	+	219	WP_000876826.1	IDEAL domain-containing protein	-
JP49775_RS04600	960949..961935	-	987	WP_000668814.1	lipoate--protein ligase	-
JP49775_RS04605	962134..962310	+	177	WP_000214898.1	YkvS family protein	-
JP49775_RS04610	962325..962927	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
JP49775_RS04615	963197..963304	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	963299..963446	-	148	-	-	Antitoxin
JP49775_RS04620	963939..964223	+	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
JP49775_RS04625	964267..966231	+	1965	WP_149036321.1	bacteriocin-associated integral membrane family protein	-
JP49775_RS04630	966234..966554	+	321	WP_000668623.1	YxeA family protein	-
JP49775_RS04635	966551..967192	+	642	WP_029549745.1	ABC transporter ATP-binding protein	-
JP49775_RS04640	967280..967570	-	291	WP_001796515.1	hypothetical protein	-
JP49775_RS04645	967711..967848	+	138	Protein_888	poly(glycerol-phosphate) alpha-glucosyltransferase	-
JP49775_RS04650	967937..968293	-	357	WP_000766009.1	DoxX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T31423 WP_000623369.1 NZ_AP017922:963197-963304 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T31423 NZ_AP017922:963197-963304 [Staphylococcus aureus]
GTGATATCTATTGCAAATGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT31423 NZ_AP017922:c963446-963299 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGTAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTGCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin